ID   CSGA_SALTI              Reviewed;         151 AA.
AC   P0A1E6; P55225;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Major curlin subunit;
DE   AltName: Full=Fimbrin SEF17;
DE   Flags: Precursor;
GN   Name=csgA; Synonyms=agfA; OrderedLocusNames=STY1181, t1776;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Curlin is the structural subunit of the curli. Curli are
CC       coiled surface structures that assemble preferentially at growth
CC       temperatures below 37 degrees Celsius. Curli can bind to fibronectin
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Fimbrium. Note=Part of the curli surface
CC       structure.
CC   -!- SIMILARITY: Belongs to the CsgA/CsgB family. {ECO:0000305}.
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DR   EMBL; AL513382; CAD08268.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO69399.1; -; Genomic_DNA.
DR   RefSeq; NP_455638.1; NC_003198.1.
DR   RefSeq; WP_000771416.1; NZ_WSUR01000018.1.
DR   AlphaFoldDB; P0A1E6; -.
DR   STRING; 220341.16502315; -.
DR   EnsemblBacteria; AAO69399; AAO69399; t1776.
DR   GeneID; 66755549; -.
DR   KEGG; stt:t1776; -.
DR   KEGG; sty:STY1181; -.
DR   PATRIC; fig|220341.7.peg.1181; -.
DR   eggNOG; ENOG5030M63; Bacteria.
DR   HOGENOM; CLU_1861613_0_0_6; -.
DR   OMA; NSEIQIY; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   InterPro; IPR009742; Curlin_rpt.
DR   Pfam; PF07012; Curlin_rpt; 4.
PE   3: Inferred from homology;
KW   Fimbrium; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000250"
FT   CHAIN           21..151
FT                   /note="Major curlin subunit"
FT                   /id="PRO_0000006372"
SQ   SEQUENCE   151 AA;  15305 MW;  B7DAC0D16B621359 CRC64;
     MKLLKVAAFA AIVVSGSALA GVVPQWGGGG NHNGGGNSSG PDSTLSIYQY GSANAALALQ
     SDARKSETTI TQSGYGNGAD VGQGADNSTI ELTQNGFRNN ATIDQWNAKN SDITVGQYGG
     NNAALVNQTA SDSSVMVRQV GFGNNATANQ Y