ID   CSGA_SALTY              Reviewed;         151 AA.
AC   P0A1E5; P55225;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Major curlin subunit;
DE   AltName: Full=Fimbrin SEF17;
DE   Flags: Precursor;
GN   Name=csgA; Synonyms=agfA; OrderedLocusNames=STM1144;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=SR-11;
RX   PubMed=9457880; DOI=10.1128/jb.180.3.722-731.1998;
RA   Romling U., Bian Z., Hammar M., Sierralta W.D., Normark S.;
RT   "Curli fibers are highly conserved between Salmonella typhimurium and
RT   Escherichia coli with respect to operon structure and regulation.";
RL   J. Bacteriol. 180:722-731(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Curlin is the structural subunit of the curli. Curli are
CC       coiled surface structures that assemble preferentially at growth
CC       temperatures below 37 degrees Celsius. Curli can bind to fibronectin.
CC   -!- SUBCELLULAR LOCATION: Fimbrium. Note=Part of the curli surface
CC       structure.
CC   -!- SIMILARITY: Belongs to the CsgA/CsgB family. {ECO:0000305}.
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DR   EMBL; AJ002301; CAA05317.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL20074.1; -; Genomic_DNA.
DR   RefSeq; NP_460115.1; NC_003197.2.
DR   RefSeq; WP_000771416.1; NC_003197.2.
DR   AlphaFoldDB; P0A1E5; -.
DR   STRING; 99287.STM1144; -.
DR   PaxDb; P0A1E5; -.
DR   PRIDE; P0A1E5; -.
DR   DNASU; 1252662; -.
DR   EnsemblBacteria; AAL20074; AAL20074; STM1144.
DR   GeneID; 1252662; -.
DR   GeneID; 66755549; -.
DR   KEGG; stm:STM1144; -.
DR   PATRIC; fig|99287.12.peg.1211; -.
DR   HOGENOM; CLU_1861613_0_0_6; -.
DR   OMA; NSEIQIY; -.
DR   PhylomeDB; P0A1E5; -.
DR   BioCyc; SENT99287:STM1144-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   InterPro; IPR009742; Curlin_rpt.
DR   Pfam; PF07012; Curlin_rpt; 4.
PE   3: Inferred from homology;
KW   Fimbrium; Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000250"
FT   CHAIN           21..151
FT                   /note="Major curlin subunit"
FT                   /id="PRO_0000006373"
SQ   SEQUENCE   151 AA;  15305 MW;  B7DAC0D16B621359 CRC64;
     MKLLKVAAFA AIVVSGSALA GVVPQWGGGG NHNGGGNSSG PDSTLSIYQY GSANAALALQ
     SDARKSETTI TQSGYGNGAD VGQGADNSTI ELTQNGFRNN ATIDQWNAKN SDITVGQYGG
     NNAALVNQTA SDSSVMVRQV GFGNNATANQ Y