ID   CSGC_ECOK1              Reviewed;         110 AA.
AC   A1A9U1;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-MAR-2010, sequence version 2.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Curli assembly protein CsgC;
DE   Flags: Precursor;
GN   Name=csgC; OrderedLocusNames=Ecok1_09370; ORFNames=APECO1_128;
OS   Escherichia coli O1:K1 / APEC.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=405955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17293413; DOI=10.1128/jb.01726-06;
RA   Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J.,
RA   Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.;
RT   "The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7
RT   shares strong similarities with human extraintestinal pathogenic E. coli
RT   genomes.";
RL   J. Bacteriol. 189:3228-3236(2007).
CC   -!- FUNCTION: Plays a role in the extracellular assembly of CsgA into thin
CC       aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE.
CC       Tafi are thought to be assembled via an extracellular nucleation-
CC       precipitation (ENP) pathway, and possibly also via an intracellular
CC       non-CsgC-dependent pathway (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CsgC/AgfC family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABJ00431.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000468; ABJ00431.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000992818.1; NC_008563.1.
DR   AlphaFoldDB; A1A9U1; -.
DR   SMR; A1A9U1; -.
DR   EnsemblBacteria; ABJ00431; ABJ00431; APECO1_128.
DR   KEGG; ecv:APECO1_128; -.
DR   HOGENOM; CLU_152585_0_0_6; -.
DR   Proteomes; UP000008216; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   InterPro; IPR014491; Curli_production_prot_CsgC.
DR   Pfam; PF10610; Tafi-CsgC; 1.
DR   PIRSF; PIRSF018100; CsgC; 1.
PE   3: Inferred from homology;
KW   Chaperone; Periplasm; Signal.
FT   SIGNAL          1..8
FT                   /evidence="ECO:0000255"
FT   CHAIN           9..110
FT                   /note="Curli assembly protein CsgC"
FT                   /id="PRO_0000391678"
SQ   SEQUENCE   110 AA;  11969 MW;  E72FCE027A82DFF8 CRC64;
     MNALLLLAAL SSQITFNTTQ QGDMYTIIPE VTLTQSCLCR VQILSLREGS SGQSQTKQEK
     TLSLPANQPI ALTKLSLNIS PDDRVKIVVT VSDGQSLHLS QQWPPSSEKS