ID   CSGC_ECOLU              Reviewed;         110 AA.
AC   B7NAR8;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-MAR-2010, sequence version 2.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Curli assembly protein CsgC;
DE   Flags: Precursor;
GN   Name=csgC; OrderedLocusNames=ECUMN_1217;
OS   Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585056;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UMN026 / ExPEC;
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA   Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA   Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA   Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA   Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA   Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
CC   -!- FUNCTION: Plays a role in the extracellular assembly of CsgA into thin
CC       aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE.
CC       Tafi are thought to be assembled via an extracellular nucleation-
CC       precipitation (ENP) pathway, and possibly also via an intracellular
CC       non-CsgC-dependent pathway (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CsgC/AgfC family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAR12426.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU928163; CAR12426.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000992818.1; NC_011751.1.
DR   AlphaFoldDB; B7NAR8; -.
DR   SMR; B7NAR8; -.
DR   STRING; 585056.ECUMN_1217; -.
DR   EnsemblBacteria; CAR12426; CAR12426; ECUMN_1217.
DR   KEGG; eum:ECUMN_1217; -.
DR   PATRIC; fig|585056.7.peg.1419; -.
DR   HOGENOM; CLU_152585_0_0_6; -.
DR   Proteomes; UP000007097; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   InterPro; IPR014491; Curli_production_prot_CsgC.
DR   Pfam; PF10610; Tafi-CsgC; 1.
DR   PIRSF; PIRSF018100; CsgC; 1.
PE   3: Inferred from homology;
KW   Chaperone; Periplasm; Signal.
FT   SIGNAL          1..8
FT                   /evidence="ECO:0000255"
FT   CHAIN           9..110
FT                   /note="Curli assembly protein CsgC"
FT                   /id="PRO_0000391677"
SQ   SEQUENCE   110 AA;  11969 MW;  E72FCE027A82DFF8 CRC64;
     MNALLLLAAL SSQITFNTTQ QGDMYTIIPE VTLTQSCLCR VQILSLREGS SGQSQTKQEK
     TLSLPANQPI ALTKLSLNIS PDDRVKIVVT VSDGQSLHLS QQWPPSSEKS