CSGC_SALTY
ID CSGC_SALTY Reviewed; 108 AA.
AC P0A1Z8; P55227;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 64.
DE RecName: Full=Curli assembly protein CsgC;
DE Flags: Precursor;
GN Name=csgC; Synonyms=agfC; OrderedLocusNames=STM1145;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=SR-11;
RX PubMed=9457880; DOI=10.1128/jb.180.3.722-731.1998;
RA Romling U., Bian Z., Hammar M., Sierralta W.D., Normark S.;
RT "Curli fibers are highly conserved between Salmonella typhimurium and
RT Escherichia coli with respect to operon structure and regulation.";
RL J. Bacteriol. 180:722-731(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Plays a role in the extracellular assembly of CsgA into thin
CC aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE.
CC Tafi are thought to be assembled via an extracellular nucleation-
CC precipitation (ENP) pathway, and possibly also via an intracellular
CC non-CsgC-dependent pathway (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CsgC/AgfC family. {ECO:0000305}.
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DR EMBL; AJ002301; CAA05318.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20075.1; -; Genomic_DNA.
DR RefSeq; NP_460116.1; NC_003197.2.
DR RefSeq; WP_000557256.1; NC_003197.2.
DR AlphaFoldDB; P0A1Z8; -.
DR SMR; P0A1Z8; -.
DR STRING; 99287.STM1145; -.
DR PaxDb; P0A1Z8; -.
DR EnsemblBacteria; AAL20075; AAL20075; STM1145.
DR GeneID; 1252663; -.
DR KEGG; stm:STM1145; -.
DR PATRIC; fig|99287.12.peg.1212; -.
DR HOGENOM; CLU_152585_0_0_6; -.
DR OMA; SNQLWFD; -.
DR PhylomeDB; P0A1Z8; -.
DR BioCyc; SENT99287:STM1145-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR InterPro; IPR014491; Curli_production_prot_CsgC.
DR Pfam; PF10610; Tafi-CsgC; 1.
DR PIRSF; PIRSF018100; CsgC; 1.
PE 3: Inferred from homology;
KW Chaperone; Periplasm; Reference proteome; Signal.
FT SIGNAL 1..8
FT /evidence="ECO:0000255"
FT CHAIN 9..108
FT /note="Curli assembly protein CsgC"
FT /id="PRO_0000021015"
SQ SEQUENCE 108 AA; 11721 MW; EF8EC3B795F4C05E CRC64;
MHTLLLLAAL SNQITFTTTQ QGDIYTVIPQ VTLNEPCVCQ VQILSVRDGV GGQSHTQQKQ
TLSLPANQPI ELSRLSVNIS SEDSVKIIVT VSDGQSLHLS QQWPPSAQ