CSGD_SALTY
ID CSGD_SALTY Reviewed; 216 AA.
AC O54294;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Probable csgAB operon transcriptional regulatory protein;
GN Name=csgD; OrderedLocusNames=STM1142;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=SR-11;
RX PubMed=9457880; DOI=10.1128/jb.180.3.722-731.1998;
RA Romling U., Bian Z., Hammar M., Sierralta W.D., Normark S.;
RT "Curli fibers are highly conserved between Salmonella typhimurium and
RT Escherichia coli with respect to operon structure and regulation.";
RL J. Bacteriol. 180:722-731(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Necessary for transcription of the csgAB operon. May have the
CC capability to respond to starvation and/or high cell density by
CC activating csgBA transcription (By similarity). {ECO:0000250}.
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DR EMBL; AJ002301; CAA05315.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20072.1; -; Genomic_DNA.
DR RefSeq; NP_460113.1; NC_003197.2.
DR RefSeq; WP_000481517.1; NC_003197.2.
DR PDB; 5XP0; X-ray; 2.00 A; A/B=2-148.
DR PDBsum; 5XP0; -.
DR AlphaFoldDB; O54294; -.
DR SMR; O54294; -.
DR STRING; 99287.STM1142; -.
DR PaxDb; O54294; -.
DR EnsemblBacteria; AAL20072; AAL20072; STM1142.
DR GeneID; 1252660; -.
DR KEGG; stm:STM1142; -.
DR PATRIC; fig|99287.12.peg.1209; -.
DR HOGENOM; CLU_000445_90_7_6; -.
DR OMA; AQTHLHE; -.
DR PhylomeDB; O54294; -.
DR BioCyc; SENT99287:STM1142-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; SSF46894; 1.
DR PROSITE; PS00622; HTH_LUXR_1; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; DNA-binding; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..216
FT /note="Probable csgAB operon transcriptional regulatory
FT protein"
FT /id="PRO_0000184144"
FT DOMAIN 149..214
FT /note="HTH luxR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT DNA_BIND 173..192
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT STRAND 8..10
FT /evidence="ECO:0007829|PDB:5XP0"
FT STRAND 12..17
FT /evidence="ECO:0007829|PDB:5XP0"
FT HELIX 21..34
FT /evidence="ECO:0007829|PDB:5XP0"
FT STRAND 37..42
FT /evidence="ECO:0007829|PDB:5XP0"
FT STRAND 54..59
FT /evidence="ECO:0007829|PDB:5XP0"
FT HELIX 60..62
FT /evidence="ECO:0007829|PDB:5XP0"
FT HELIX 65..76
FT /evidence="ECO:0007829|PDB:5XP0"
FT STRAND 83..88
FT /evidence="ECO:0007829|PDB:5XP0"
FT STRAND 91..93
FT /evidence="ECO:0007829|PDB:5XP0"
FT HELIX 95..99
FT /evidence="ECO:0007829|PDB:5XP0"
FT STRAND 104..107
FT /evidence="ECO:0007829|PDB:5XP0"
FT HELIX 114..125
FT /evidence="ECO:0007829|PDB:5XP0"
FT HELIX 133..140
FT /evidence="ECO:0007829|PDB:5XP0"
SQ SEQUENCE 216 AA; 24846 MW; 2381AEEA00B900E0 CRC64;
MFNEVHSSHG HTLLLITKPS LQATALLQHL KQSLAITGKL HNIQRSLEDI SAGCIVLMDM
MEADKKLIHY WQDNLSRKNN NIKTLLLNTP DDYPYREIEN WPHINGVFYA TEDQEHVVSG
LQGILRGECY FSQKLASYLI THSGNYRYNS TESALLTHRE KEILNKLRIG ASNNEIARSL
FISENTVKTH LYNLFKKIAV KNRTQAVSWA NDNLRR