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CSGD_SALTY
ID   CSGD_SALTY              Reviewed;         216 AA.
AC   O54294;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Probable csgAB operon transcriptional regulatory protein;
GN   Name=csgD; OrderedLocusNames=STM1142;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=SR-11;
RX   PubMed=9457880; DOI=10.1128/jb.180.3.722-731.1998;
RA   Romling U., Bian Z., Hammar M., Sierralta W.D., Normark S.;
RT   "Curli fibers are highly conserved between Salmonella typhimurium and
RT   Escherichia coli with respect to operon structure and regulation.";
RL   J. Bacteriol. 180:722-731(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Necessary for transcription of the csgAB operon. May have the
CC       capability to respond to starvation and/or high cell density by
CC       activating csgBA transcription (By similarity). {ECO:0000250}.
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DR   EMBL; AJ002301; CAA05315.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL20072.1; -; Genomic_DNA.
DR   RefSeq; NP_460113.1; NC_003197.2.
DR   RefSeq; WP_000481517.1; NC_003197.2.
DR   PDB; 5XP0; X-ray; 2.00 A; A/B=2-148.
DR   PDBsum; 5XP0; -.
DR   AlphaFoldDB; O54294; -.
DR   SMR; O54294; -.
DR   STRING; 99287.STM1142; -.
DR   PaxDb; O54294; -.
DR   EnsemblBacteria; AAL20072; AAL20072; STM1142.
DR   GeneID; 1252660; -.
DR   KEGG; stm:STM1142; -.
DR   PATRIC; fig|99287.12.peg.1209; -.
DR   HOGENOM; CLU_000445_90_7_6; -.
DR   OMA; AQTHLHE; -.
DR   PhylomeDB; O54294; -.
DR   BioCyc; SENT99287:STM1142-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   1: Evidence at protein level;
KW   3D-structure; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..216
FT                   /note="Probable csgAB operon transcriptional regulatory
FT                   protein"
FT                   /id="PRO_0000184144"
FT   DOMAIN          149..214
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   DNA_BIND        173..192
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   STRAND          8..10
FT                   /evidence="ECO:0007829|PDB:5XP0"
FT   STRAND          12..17
FT                   /evidence="ECO:0007829|PDB:5XP0"
FT   HELIX           21..34
FT                   /evidence="ECO:0007829|PDB:5XP0"
FT   STRAND          37..42
FT                   /evidence="ECO:0007829|PDB:5XP0"
FT   STRAND          54..59
FT                   /evidence="ECO:0007829|PDB:5XP0"
FT   HELIX           60..62
FT                   /evidence="ECO:0007829|PDB:5XP0"
FT   HELIX           65..76
FT                   /evidence="ECO:0007829|PDB:5XP0"
FT   STRAND          83..88
FT                   /evidence="ECO:0007829|PDB:5XP0"
FT   STRAND          91..93
FT                   /evidence="ECO:0007829|PDB:5XP0"
FT   HELIX           95..99
FT                   /evidence="ECO:0007829|PDB:5XP0"
FT   STRAND          104..107
FT                   /evidence="ECO:0007829|PDB:5XP0"
FT   HELIX           114..125
FT                   /evidence="ECO:0007829|PDB:5XP0"
FT   HELIX           133..140
FT                   /evidence="ECO:0007829|PDB:5XP0"
SQ   SEQUENCE   216 AA;  24846 MW;  2381AEEA00B900E0 CRC64;
     MFNEVHSSHG HTLLLITKPS LQATALLQHL KQSLAITGKL HNIQRSLEDI SAGCIVLMDM
     MEADKKLIHY WQDNLSRKNN NIKTLLLNTP DDYPYREIEN WPHINGVFYA TEDQEHVVSG
     LQGILRGECY FSQKLASYLI THSGNYRYNS TESALLTHRE KEILNKLRIG ASNNEIARSL
     FISENTVKTH LYNLFKKIAV KNRTQAVSWA NDNLRR
 
 
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