CSG_METJA
ID CSG_METJA Reviewed; 558 AA.
AC Q58232;
DT 26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=S-layer protein {ECO:0000303|PubMed:12382110};
DE AltName: Full=Cell surface glycoprotein {ECO:0000305};
DE AltName: Full=Surface layer protein;
DE Flags: Precursor;
GN Name=sla; Synonyms=slmJ1; OrderedLocusNames=MJ0822;
OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS 10045 / NBRC 100440) (Methanococcus jannaschii).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=243232;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT jannaschii.";
RL Science 273:1058-1073(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 29-38, FUNCTION, AND
RP SUBCELLULAR LOCATION.
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX PubMed=12382110; DOI=10.1007/s00792-001-0264-1;
RA Akca E., Claus H., Schultz N., Karbach G., Schlott B., Debaerdemaeker T.,
RA Declercq J.P., Konig H.;
RT "Genes and derived amino acid sequences of S-layer proteins from
RT mesophilic, thermophilic, and extremely thermophilic methanococci.";
RL Extremophiles 6:351-358(2002).
RN [3]
RP PROTEIN SEQUENCE OF 29-39.
RC STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RA Graham D.E.;
RT "Archaeal gene identification.";
RL Thesis (2000), University of Illinois, United States.
CC -!- FUNCTION: S-layer protein. The S-layer is a paracrystalline mono-
CC layered assembly of proteins which coat the surface of the cell.
CC {ECO:0000269|PubMed:12382110}.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall, S-layer
CC {ECO:0000269|PubMed:12382110}.
CC -!- SIMILARITY: Belongs to the Mj S-layer protein family. {ECO:0000305}.
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DR EMBL; L77117; AAB98821.1; -; Genomic_DNA.
DR EMBL; AJ311636; CAC84089.1; -; Genomic_DNA.
DR PIR; F64402; F64402.
DR RefSeq; WP_010870333.1; NC_000909.1.
DR AlphaFoldDB; Q58232; -.
DR SMR; Q58232; -.
DR DNASU; 1451705; -.
DR EnsemblBacteria; AAB98821; AAB98821; MJ_0822.
DR GeneID; 1451705; -.
DR KEGG; mja:MJ_0822; -.
DR eggNOG; arCOG03418; Archaea.
DR HOGENOM; CLU_016296_0_0_2; -.
DR InParanoid; Q58232; -.
DR OMA; LMFKEGT; -.
DR OrthoDB; 37561at2157; -.
DR PhylomeDB; Q58232; -.
DR Proteomes; UP000000805; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0030115; C:S-layer; IEA:UniProtKB-SubCell.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR InterPro; IPR022651; S_layer_C.
DR InterPro; IPR006454; S_layer_MJ.
DR InterPro; IPR022650; S_layer_N.
DR Pfam; PF05124; S_layer_C; 1.
DR Pfam; PF05123; S_layer_N; 1.
DR TIGRFAMs; TIGR01564; S_layer_MJ; 1.
PE 1: Evidence at protein level;
KW Cell wall; Cell wall biogenesis/degradation; Direct protein sequencing;
KW Glycoprotein; Reference proteome; S-layer; Secreted; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000269|PubMed:12382110, ECO:0000269|Ref.3"
FT CHAIN 29..558
FT /note="S-layer protein"
FT /id="PRO_0000032620"
FT CARBOHYD 112
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 138
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 158
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 197
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 226
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 291
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 374
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 558 AA; 60548 MW; CF46C69302BBFB01 CRC64;
MAMSLKKIGA IAVGGAMVAT ALASGVAAEV TTSGFSDYKE LKDILVKDGQ PNCYVVVGAD
APSTMDVVSA ADIAAKIGSL CYKEGTVEDG SADITVHAEA NSDDFDLKKD WNNSAMPANA
YALFVAASDG DYSEKFENDT GKPSFMDNGV LGDADKINKT VDLGDIATMM KVDDVDPSDW
YDSDDDAGEI VMVELKNDTS DGFTVYKKNM LYETLVYKDD EENFANTTKM EEGMRIPFLG
KEMVVVDIDK DDDAIYLGTP VYDGIIKEGE TYDLGNGYQV KIKAILKTTV NNTDVYKVDV
QILKDGKVVA EKYDKAPLEL EYKDDVGVTV HKAWENVGGD YGYAELVISK DLKKLELDEE
YVTDWKAYAV LNDNGTMKLE DDLNDNNVDK VVGIALRYDG DKLDDLDSGD EVDILDYVKF
KLDDEDSNDK LKVYFSMDKD VDATLNIGEK VKALNAEVKL KDIKANAVEP VSLTAPIAKL
DTEVSLDTAD KNLVLVGGPV ANKLTKELVD AGKLALDNNS PATIALIPDA ANGHDVIVVA
GGDREKTREA ALELIKNL
