ID   ACPX_STRCN              Reviewed;          86 AA.
AC   Q02570;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Curamycin polyketide synthase acyl carrier protein;
DE            Short=ACP;
GN   Name=curE;
OS   Streptomyces cyaneus (Streptomyces curacoi).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1904;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 13385 / CBS 484.68 / DSM 40107 / JCM 4219 / NBRC 12761 / NRRL
RC   B-2901 / VKM Ac-621;
RX   PubMed=1644304; DOI=10.1016/0378-1119(92)90501-f;
RA   Bergh S., Uhlen M.;
RT   "Analysis of a polyketide synthesis-encoding gene cluster of Streptomyces
RT   curacoi.";
RL   Gene 117:131-136(1992).
CC   -!- FUNCTION: Acyl carrier protein.
CC   -!- PATHWAY: Antibiotic biosynthesis; curamycin biosynthesis.
CC   -!- PTM: 4'-phosphopantetheine is transferred from CoA to a specific serine
CC       of the apo-ACP-like protein. {ECO:0000305}.
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DR   EMBL; X62518; CAA44382.1; -; Genomic_DNA.
DR   PIR; JC1214; JC1214.
DR   AlphaFoldDB; Q02570; -.
DR   SMR; Q02570; -.
DR   UniPathway; UPA00176; -.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1200.10; -; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   Pfam; PF00550; PP-binding; 1.
DR   SUPFAM; SSF47336; SSF47336; 1.
DR   PROSITE; PS50075; CARRIER; 1.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   3: Inferred from homology;
KW   Antibiotic biosynthesis; Phosphopantetheine; Phosphoprotein.
FT   CHAIN           1..86
FT                   /note="Curamycin polyketide synthase acyl carrier protein"
FT                   /id="PRO_0000180251"
FT   DOMAIN          7..86
FT                   /note="Carrier"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00258"
FT   MOD_RES         44
FT                   /note="O-(pantetheine 4'-phosphoryl)serine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00258"
SQ   SEQUENCE   86 AA;  9189 MW;  F53BE98A882CEE2A CRC64;
     MTTEVTQVTV EELATLMKKA AGVTVDPRDL ERRANGFADF GLDSLGLLGI VGELENRYAR
     ALHRRGTCKS PRAFLDVVNG ALASGA