ID   ACPY_STRAW              Reviewed;          87 AA.
AC   Q93HC3;
DT   02-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Polyketide-8 synthase acyl carrier protein 2;
DE            Short=ACP 2;
GN   OrderedLocusNames=SAV_3656;
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=227882;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
CC   -!- FUNCTION: Acyl carrier protein.
CC   -!- PTM: 4'-phosphopantetheine is transferred from CoA to a specific serine
CC       of the apo-ACP-like protein. {ECO:0000305}.
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DR   EMBL; AB070946; BAB69265.1; -; Genomic_DNA.
DR   EMBL; BA000030; BAC71368.1; -; Genomic_DNA.
DR   RefSeq; WP_010985087.1; NZ_JZJK01000090.1.
DR   AlphaFoldDB; Q93HC3; -.
DR   SMR; Q93HC3; -.
DR   STRING; 227882.SAV_3656; -.
DR   EnsemblBacteria; BAC71368; BAC71368; SAVERM_3656.
DR   KEGG; sma:SAVERM_3656; -.
DR   eggNOG; COG0236; Bacteria.
DR   HOGENOM; CLU_108696_7_2_11; -.
DR   OMA; LMAMEVM; -.
DR   OrthoDB; 1943389at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR   GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR   GO; GO:0030639; P:polyketide biosynthetic process; IEA:UniProt.
DR   Gene3D; 1.10.1200.10; -; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   SUPFAM; SSF47336; SSF47336; 1.
DR   PROSITE; PS50075; CARRIER; 1.
PE   3: Inferred from homology;
KW   Phosphopantetheine; Phosphoprotein; Reference proteome.
FT   CHAIN           1..87
FT                   /note="Polyketide-8 synthase acyl carrier protein 2"
FT                   /id="PRO_0000180259"
FT   DOMAIN          8..83
FT                   /note="Carrier"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00258"
FT   MOD_RES         43
FT                   /note="O-(pantetheine 4'-phosphoryl)serine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00258"
SQ   SEQUENCE   87 AA;  9681 MW;  30B02FC195FC1819 CRC64;
     MPETTTTALD KEQLRELVAD VLDLDVAEVT DDADFMEDLD VDSLMALEIT VRLEKEYGVR
     LAEAELTSIT SLQGTYELLT SKLGDTR