CSK2B_SPOFR
ID CSK2B_SPOFR Reviewed; 221 AA.
AC O76485;
DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 68.
DE RecName: Full=Casein kinase II subunit beta;
DE Short=CK II beta;
OS Spodoptera frugiperda (Fall armyworm).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC Noctuidae; Amphipyrinae; Spodoptera.
OX NCBI_TaxID=7108;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Ebel W., Steplewski A., Robertson N.M., Alnemri E.S., Litwack G.;
RT "Identification, cloning and expression of Spodoptera frugiperda casein
RT kinase II.";
RL Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Participates in Wnt signaling. Plays a complex role in
CC regulating the basal catalytic activity of the alpha subunit (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Tetramer of two alpha and two beta subunits.
CC -!- PTM: Phosphorylated by alpha subunit. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the casein kinase 2 subunit beta family.
CC {ECO:0000305}.
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DR EMBL; AF071211; AAC24042.1; -; mRNA.
DR AlphaFoldDB; O76485; -.
DR SMR; O76485; -.
DR GO; GO:0005956; C:protein kinase CK2 complex; IEA:InterPro.
DR GO; GO:0019887; F:protein kinase regulator activity; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1820.10; -; 1.
DR InterPro; IPR016149; Casein_kin_II_reg-sub_N.
DR InterPro; IPR035991; Casein_kinase_II_beta-like.
DR InterPro; IPR000704; Casein_kinase_II_reg-sub.
DR PANTHER; PTHR11740; PTHR11740; 1.
DR Pfam; PF01214; CK_II_beta; 1.
DR PRINTS; PR00472; CASNKINASEII.
DR SMART; SM01085; CK_II_beta; 1.
DR SUPFAM; SSF57798; SSF57798; 1.
DR PROSITE; PS01101; CK2_BETA; 1.
PE 2: Evidence at transcript level;
KW Phosphoprotein; Wnt signaling pathway.
FT CHAIN 1..221
FT /note="Casein kinase II subunit beta"
FT /id="PRO_0000068247"
FT MOD_RES 2
FT /note="Phosphoserine; by autocatalysis"
FT /evidence="ECO:0000305"
SQ SEQUENCE 221 AA; 25376 MW; 3317BB391D708936 CRC64;
MSSSEEVSWI SWFCGLRGNE FFCEVDEDYI NDKFNLTGLN EQVPHYRQAL DMILDLEPDD
DLDDNPNQSD LVEQASEILY GLIHARYILT NRGIGQMLEK FQAGDFGHCP RVYCECQPML
PLGLSDVPGE AMVKLYCPRC MDVYTPKSSR HHHTDGAYFG TGFPHMVFMV HPEYRPKRPA
SQFVPRLYGF KIHPLAYQIQ QQAAANFKAP LRSLSYNNGK R