CSLA6_ORYSJ
ID CSLA6_ORYSJ Reviewed; 574 AA.
AC Q6Z2T9; Q0DXM1; Q0DXM2; Q8W1N1; Q944E6;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2008, sequence version 2.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Probable glucomannan 4-beta-mannosyltransferase 6 {ECO:0000305};
DE EC=2.4.1.32 {ECO:0000250|UniProtKB:Q7PC76};
DE AltName: Full=Cellulose synthase-like protein A6 {ECO:0000303|PubMed:11842136};
DE Short=OsCslA6 {ECO:0000303|PubMed:11842136};
DE AltName: Full=Glucomannan synthase {ECO:0000305};
DE AltName: Full=Mannan synthase 6 {ECO:0000305};
GN Name=CSLA6 {ECO:0000303|PubMed:11842136};
GN OrderedLocusNames=Os02g0744600/Os02g0744650, Os02g0744500, LOC_Os02g51060;
GN ORFNames=OJ1118_G04.6, OJ1734_E02.33;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], NUCLEOTIDE SEQUENCE [MRNA] OF 464-574,
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11842136; DOI=10.1104/pp.010875;
RA Hazen S.P., Scott-Craig J.S., Walton J.D.;
RT "Cellulose synthase-like genes of rice.";
RL Plant Physiol. 128:336-340(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
CC -!- FUNCTION: Probable mannan synthase which consists of a 4-beta-
CC mannosyltransferase activity on mannan using GDP-mannose. The beta-1,4-
CC mannan product is the backbone for galactomannan synthesis by
CC galactomannan galactosyltransferase. Galactomannan is a noncellulosic
CC polysaccharides of plant cell wall. {ECO:0000250|UniProtKB:Q7PC76}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GDP-mannose + (glucomannan)n = GDP + (glucomannan)n+1.;
CC EC=2.4.1.32; Evidence={ECO:0000250|UniProtKB:Q7PC76};
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi-
CC pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. Plant
CC cellulose synthase-like A subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD15538.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAD16122.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAF10017.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF432498; AAL25127.1; -; Genomic_DNA.
DR EMBL; AF435648; AAL38533.1; -; mRNA.
DR EMBL; AP004114; BAD15538.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP005297; BAD16122.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008208; BAF10017.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014958; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; Q6Z2T9; -.
DR STRING; 4530.OS02T0744650-00; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR PaxDb; Q6Z2T9; -.
DR PRIDE; Q6Z2T9; -.
DR eggNOG; ENOG502QR7J; Eukaryota.
DR InParanoid; Q6Z2T9; -.
DR PlantReactome; R-OSA-1119573; Dolichyl-diphosphooligosaccharide biosynthesis.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0047259; F:glucomannan 4-beta-mannosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0016757; F:glycosyltransferase activity; IBA:GO_Central.
DR GO; GO:0051753; F:mannan synthase activity; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR Gene3D; 3.90.550.10; -; 1.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 2: Evidence at transcript level;
KW Cell wall biogenesis/degradation; Glycosyltransferase; Golgi apparatus;
KW Membrane; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..574
FT /note="Probable glucomannan 4-beta-mannosyltransferase 6"
FT /id="PRO_0000319377"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 412..432
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 437..457
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 523..543
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 548..568
FT /note="Helical"
FT /evidence="ECO:0000255"
FT ACT_SITE 180
FT /evidence="ECO:0000255"
FT ACT_SITE 333
FT /evidence="ECO:0000255"
FT BINDING 239
FT /ligand="substrate"
FT /evidence="ECO:0000255"
FT BINDING 241
FT /ligand="substrate"
FT /evidence="ECO:0000255"
SQ SEQUENCE 574 AA; 65561 MW; E6255FE708ADE178 CRC64;
MQGSSTSILH FVPSDPTSTS VLDFLSPTPR GTSPVHDRRL HAGDLALRAG GDRLLVADTV
AAVVESLVQA WRQVRMELLV PLLRGAVVAC MVMSVIVLAE KVFLGVVSAV VKLLRRRPAR
LYRCDPVVVE DDDEAGRASF PMVLVQIPMY NEKEVYQLSI GAACRLTWPA DRLIVQVLDD
STDAIVKELV RKECERWGKK GINVKYETRK DRAGYKAGNL REGMRRGYVQ GCEFVAMLDA
DFQPPPDFLL KTVPFLVHNP RLALVQTRWE FVNANDCLLT RMQEMSMDYH FKVEQEAGSS
LCNFFGYNGT AGVWRRQVID ESGGWEDRTT AEDMDLALRA GLLGWEFVYV GSIKVKSELP
STLKAYRSQQ HRWSCGPALL FKKMFWEILA AKKVSFWKKL YMTYDFFIAR RIISTFFTFF
FFSVLLPMKV FFPEVQIPLW ELILIPTAII LLHSVGTPRS IHLIILWFLF ENVMALHRLK
ATLIGFFEAG RANEWIVTQK LGNIQKLKSI VRVTKNCRFK DRFHCLELFI GGFLLTSACY
DYLYRDDIFY IFLLSQSIIY FAIGFEFMGV SVSS
