CSLAB_ORYSJ
ID CSLAB_ORYSJ Reviewed; 570 AA.
AC Q6YWK8; Q0J5H2;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=Probable glucomannan 4-beta-mannosyltransferase 11 {ECO:0000305};
DE EC=2.4.1.32 {ECO:0000250|UniProtKB:Q7PC76};
DE AltName: Full=Cellulose synthase-like protein A11 {ECO:0000303|PubMed:11842136};
DE Short=OsCslA11 {ECO:0000303|PubMed:11842136};
DE AltName: Full=Glucomannan synthase {ECO:0000305};
DE AltName: Full=Mannan synthase 11 {ECO:0000305};
GN Name=CSLA11 {ECO:0000303|PubMed:11842136};
GN OrderedLocusNames=Os08g0434500, LOC_Os08g33740;
GN ORFNames=P0413H11.13, P0431A03.35;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11842136; DOI=10.1104/pp.010875;
RA Hazen S.P., Scott-Craig J.S., Walton J.D.;
RT "Cellulose synthase-like genes of rice.";
RL Plant Physiol. 128:336-340(2002).
CC -!- FUNCTION: Probable mannan synthase which consists of a 4-beta-
CC mannosyltransferase activity on mannan using GDP-mannose. The beta-1,4-
CC mannan product is the backbone for galactomannan synthesis by
CC galactomannan galactosyltransferase. Galactomannan is a noncellulosic
CC polysaccharides of plant cell wall. {ECO:0000250|UniProtKB:Q7PC76}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GDP-mannose + (glucomannan)n = GDP + (glucomannan)n+1.;
CC EC=2.4.1.32; Evidence={ECO:0000250|UniProtKB:Q7PC76};
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi-
CC pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. Plant
CC cellulose synthase-like A subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF23793.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP004666; BAD09847.1; -; Genomic_DNA.
DR EMBL; AP005757; BAD10623.1; -; Genomic_DNA.
DR EMBL; AP008214; BAF23793.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014964; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015648204.1; XM_015792718.1.
DR AlphaFoldDB; Q6YWK8; -.
DR STRING; 4530.OS08T0434632-01; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR PaxDb; Q6YWK8; -.
DR PRIDE; Q6YWK8; -.
DR GeneID; 4345658; -.
DR KEGG; osa:4345658; -.
DR InParanoid; Q6YWK8; -.
DR OrthoDB; 559375at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0047259; F:glucomannan 4-beta-mannosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0016757; F:glycosyltransferase activity; IBA:GO_Central.
DR GO; GO:0051753; F:mannan synthase activity; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR Gene3D; 3.90.550.10; -; 1.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 2: Evidence at transcript level;
KW Cell wall biogenesis/degradation; Glycosyltransferase; Golgi apparatus;
KW Membrane; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..570
FT /note="Probable glucomannan 4-beta-mannosyltransferase 11"
FT /id="PRO_0000319380"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 389..409
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 412..432
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 522..542
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 548..568
FT /note="Helical"
FT /evidence="ECO:0000255"
FT ACT_SITE 157
FT /evidence="ECO:0000255"
FT ACT_SITE 310
FT /evidence="ECO:0000255"
FT BINDING 216
FT /ligand="substrate"
FT /evidence="ECO:0000255"
FT BINDING 218
FT /ligand="substrate"
FT /evidence="ECO:0000255"
SQ SEQUENCE 570 AA; 63947 MW; E04D3FC6C83971A7 CRC64;
MSSSGGGGVA EEVARLWGEL PVRVVWAAVA AQWAAAAAAA RAAVVVPAVR ALVAVSLAMT
VMILAEKLFV AAVCLAVRAF RLRPDRRYKW LPIGAAAAAA SSEDDEESGL VAAAAAFPMV
LVQIPMFNER EVYKLSIGAA CSLDWPSDRV VIQVLDDSTD LVVKDLVEKE CQKWQGKGVN
IKYEVRGNRK GYKAGALKEG LKHDYVKECE YIAMFDADFQ PESDFLLRTV PFLVHNSEIA
LVQTRWKFVN ANECLLTRFQ EMSLDYHFKY EQEAGSSVYS FFGFNGTAGV WRIAAIDDAG
GWKDRTTVED MDLAVRATLQ GWKFVYVGDV KVKSELPSTF KAYRFQQHRW SCGPANLFKK
MMVEILENKK VSFWNKIHLW YDFFFVGKIA AHTVTFIYYC FVIPVSVWLP EIEIPLWGVV
YVPTVITLCK AVGTPSSFHL VILWVLFENV MSLHRIKAAV TGILEAGRVN EWVVTEKLGD
ANKTKPDTNG SDAVKVIDVE LTTPLIPKLK KRRTRFWDKY HYSEIFVGIC IILSGFYDVL
YAKKGYYIFL FIQGLAFLIV GFDYIGVCPP
