CSLB1_ARATH
ID CSLB1_ARATH Reviewed; 757 AA.
AC O80898;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2008, sequence version 2.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Cellulose synthase-like protein B1;
DE Short=AtCslB1;
DE EC=2.4.1.-;
GN Name=CSLB1; OrderedLocusNames=At2g32610; ORFNames=T26B15.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11027699; DOI=10.1104/pp.124.2.495;
RA Richmond T.A., Somerville C.R.;
RT "The cellulose synthase superfamily.";
RL Plant Physiol. 124:495-498(2000).
RN [4]
RP TISSUE SPECIFICITY.
RX PubMed=11554468; DOI=10.1023/a:1010627314782;
RA Richmond T.A., Somerville C.R.;
RT "Integrative approaches to determining Csl function.";
RL Plant Mol. Biol. 47:131-143(2001).
CC -!- FUNCTION: Thought to be a Golgi-localized beta-glycan synthase that
CC polymerize the backbones of noncellulosic polysaccharides
CC (hemicelluloses) of plant cell wall.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi-
CC pass membrane protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in young seedlings, primarily in the
CC vascular tissue. {ECO:0000269|PubMed:11554468}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. Plant
CC cellulose synthase-like B subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC25943.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC004681; AAC25943.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC08705.1; -; Genomic_DNA.
DR PIR; T02560; T02560.
DR RefSeq; NP_180820.2; NM_128820.3.
DR AlphaFoldDB; O80898; -.
DR SMR; O80898; -.
DR STRING; 3702.AT2G32610.1; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR PaxDb; O80898; -.
DR PRIDE; O80898; -.
DR ProteomicsDB; 220360; -.
DR EnsemblPlants; AT2G32610.1; AT2G32610.1; AT2G32610.
DR GeneID; 817821; -.
DR Gramene; AT2G32610.1; AT2G32610.1; AT2G32610.
DR KEGG; ath:AT2G32610; -.
DR Araport; AT2G32610; -.
DR TAIR; locus:2060285; AT2G32610.
DR eggNOG; ENOG502QTT0; Eukaryota.
DR HOGENOM; CLU_001418_3_3_1; -.
DR InParanoid; O80898; -.
DR OMA; WENKERL; -.
DR OrthoDB; 267925at2759; -.
DR PhylomeDB; O80898; -.
DR BioCyc; ARA:AT2G32610-MON; -.
DR PRO; PR:O80898; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80898; baseline and differential.
DR Genevisible; O80898; AT.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0016760; F:cellulose synthase (UDP-forming) activity; IEA:InterPro.
DR GO; GO:0051753; F:mannan synthase activity; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:InterPro.
DR GO; GO:0009833; P:plant-type primary cell wall biogenesis; IBA:GO_Central.
DR Gene3D; 3.90.550.10; -; 1.
DR InterPro; IPR005150; Cellulose_synth.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF03552; Cellulose_synt; 2.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 2: Evidence at transcript level;
KW Cell wall biogenesis/degradation; Coiled coil; Glycosyltransferase;
KW Golgi apparatus; Membrane; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..757
FT /note="Cellulose synthase-like protein B1"
FT /id="PRO_0000319335"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 533..553
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 569..589
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 615..635
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 674..694
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 710..730
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 737..757
FT /note="Helical"
FT /evidence="ECO:0000255"
FT COILED 186..216
FT /evidence="ECO:0000255"
FT ACT_SITE 136
FT /evidence="ECO:0000255"
FT ACT_SITE 462
FT /evidence="ECO:0000255"
SQ SEQUENCE 757 AA; 85061 MW; E9818D765D0538F3 CRC64;
MADSSFSLPP LCERISYTNY FLRAVYLTVL GLFFSLLLHR IRHTSEYDNV WLVAFFCESC
FFLVCLLITC LKWSPADTKP FPDRLDERVH DLPSVDMFVP TADPVREPPI MVVDTVLSLL
AVNYPANKLA CYVSDDGCSP LTYFSLKEAS KFAKIWVPFC KKYNTRVRAP SRYFLKPISV
ATEDYEFNRD WEKTKREYEK LRRKVEDATG DSHMLDVEDD FEAFSNTKPN DHSTLVKVVW
ENKGGVGDEK EIPHIIYISR EKRPNYVHNQ KCGAMNFLAR VSGLMTNAPY ILNVDCDMYA
NDADVVRQAM CILLQESLNM KHCAFVQFRQ EFYDSSTELI VVLQSHLGRG IAGIQGPIYI
GSGCVHTRRV MYGLSPDDFE VDGSLSSVAT REFLVKDSLA RRFGNSKEMM KSVVDAIQRN
PNPQNILTNS IEAAREVGHC QYEYQTSWGN TIGWLYDSVA EDLNTSIGIH SRGWTSSYIS
PDTPAFLGSM PAGVPEALLQ QRRWATGWIE ILFNKQSPLR GLFSKKIRFR QRLAYLCIIT
CLRSIPELIY CLLPAYCLLH NSTLFPKGLY LGITVTLVGI HCLYTLWEFM SLGYSVQSWL
VSQSVWRIVA TSSWLFSIFD ITLKLLGISE TVFIITKKTV AGTKSALGSG PSQGEDVGPN
SDLFKFEFDG SLCFLPGTFI VLVNIAALAV FSVGLQRSSY SHEGGGSGLA EACGCVLVMM
LFLPFLMGLF KKGKYGTPLS TLSIAGFLAV LFVVFSV
