CSLB2_ARATH
ID CSLB2_ARATH Reviewed; 757 AA.
AC O80899;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Cellulose synthase-like protein B2;
DE Short=AtCslB2;
DE EC=2.4.1.-;
GN Name=CSLB2; OrderedLocusNames=At2g32620; ORFNames=T26B15.18;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11027699; DOI=10.1104/pp.124.2.495;
RA Richmond T.A., Somerville C.R.;
RT "The cellulose synthase superfamily.";
RL Plant Physiol. 124:495-498(2000).
RN [4]
RP TISSUE SPECIFICITY.
RX PubMed=11554468; DOI=10.1023/a:1010627314782;
RA Richmond T.A., Somerville C.R.;
RT "Integrative approaches to determining Csl function.";
RL Plant Mol. Biol. 47:131-143(2001).
CC -!- FUNCTION: Thought to be a Golgi-localized beta-glycan synthase that
CC polymerize the backbones of noncellulosic polysaccharides
CC (hemicelluloses) of plant cell wall.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi-
CC pass membrane protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in young seedlings, primarily in the root
CC vascular tissue. {ECO:0000269|PubMed:11554468}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. Plant
CC cellulose synthase-like B subfamily. {ECO:0000305}.
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DR EMBL; AC004681; AAC25944.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08706.1; -; Genomic_DNA.
DR PIR; T02561; T02561.
DR RefSeq; NP_180821.1; NM_128821.2.
DR AlphaFoldDB; O80899; -.
DR SMR; O80899; -.
DR STRING; 3702.AT2G32620.1; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR PaxDb; O80899; -.
DR PRIDE; O80899; -.
DR EnsemblPlants; AT2G32620.1; AT2G32620.1; AT2G32620.
DR GeneID; 817822; -.
DR Gramene; AT2G32620.1; AT2G32620.1; AT2G32620.
DR KEGG; ath:AT2G32620; -.
DR Araport; AT2G32620; -.
DR TAIR; locus:2060216; AT2G32620.
DR eggNOG; ENOG502QTT0; Eukaryota.
DR HOGENOM; CLU_001418_3_3_1; -.
DR InParanoid; O80899; -.
DR OMA; AGCEYEC; -.
DR OrthoDB; 267925at2759; -.
DR PhylomeDB; O80899; -.
DR BioCyc; ARA:AT2G32620-MON; -.
DR PRO; PR:O80899; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80899; baseline and differential.
DR Genevisible; O80899; AT.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0016760; F:cellulose synthase (UDP-forming) activity; IEA:InterPro.
DR GO; GO:0051753; F:mannan synthase activity; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:InterPro.
DR GO; GO:0009833; P:plant-type primary cell wall biogenesis; IBA:GO_Central.
DR Gene3D; 3.90.550.10; -; 1.
DR InterPro; IPR005150; Cellulose_synth.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF03552; Cellulose_synt; 2.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 2: Evidence at transcript level;
KW Cell wall biogenesis/degradation; Glycosyltransferase; Golgi apparatus;
KW Membrane; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..757
FT /note="Cellulose synthase-like protein B2"
FT /id="PRO_0000319336"
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 48..68
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 533..555
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 568..588
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 607..627
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 672..692
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 704..724
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 735..755
FT /note="Helical"
FT /evidence="ECO:0000255"
FT ACT_SITE 136
FT /evidence="ECO:0000255"
FT ACT_SITE 461
FT /evidence="ECO:0000255"
SQ SEQUENCE 757 AA; 84261 MW; 2A04FCB22C8D2CD7 CRC64;
MADSSCSLPP LYENISYKSY ILRAVDLTIL GLLFSLLLHR ILYMSQNGII WLVAFLCESC
FSFVWLLSTC TKWSPAETKP YPDRLDERVY DLPSVDMFVP TADPVREPPI MVVNTVLSLL
AVNYPANKLA CYVSDDGCSP LTYFSLKEAS KFAKIWVPFC KKYNLKVRAP FRYFLNPFAA
TEGSEFSRDW EMTKREYEKL CRKVEDATGD SHLLGTDNEL EAFSNTKPND HSTIIKVVWE
NKGGVGDEKE VPHIVYISRE KRPNYLHHYK AGAMNFLARV SGLMTNAPYM LNVDCDMYAN
EADVVRQAMC IFLQKSQNQN HCAFVQFPQE FYDSNTIKLT VIKSYMGRGI AGIQGPINVG
SGCFHSRRVM YGLSPDELED NGSLSSVATR ELLAEDSLSS GFGNSKEMVT SVVEALQRKP
NPQNILTNSI EAAQEVGHCD YESQTSWGKT IGWLYDSMSE DMNTSIGIHS RGWTSSYIAP
DPPAFLGSMP PGGLEAMIQQ RRWATGSIEV LFNKQSPLLG LFCRKLRFRQ RVAYLCVSIC
VRSIPELIYC LLPAYCLLHN SALFPKGLCL GITMLLAGMH CLYTLWEFMC LGHSIQSWYV
SQSFWRIVAT SSWLFSIFDI ILKLLGLSKN VFLVSKKTMP VETMSGSGIG PSQREDDGPN
SGKTEFDGSL YFLPGTFIVL VNLAALVGVF VGLQRSSYSH GGGGSGLGEA CACILVVMLF
FPFLKGLFAK GKYGIPLSTL SKAGFLAVSF VVFSVGN
