CSLB3_ARATH
ID CSLB3_ARATH Reviewed; 755 AA.
AC Q8RX83; O80890;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Cellulose synthase-like protein B3;
DE Short=AtCslB3;
DE EC=2.4.1.-;
GN Name=CSLB3; OrderedLocusNames=At2g32530; ORFNames=T26B15.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11027699; DOI=10.1104/pp.124.2.495;
RA Richmond T.A., Somerville C.R.;
RT "The cellulose synthase superfamily.";
RL Plant Physiol. 124:495-498(2000).
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=11554468; DOI=10.1023/a:1010627314782;
RA Richmond T.A., Somerville C.R.;
RT "Integrative approaches to determining Csl function.";
RL Plant Mol. Biol. 47:131-143(2001).
CC -!- FUNCTION: Thought to be a Golgi-localized beta-glycan synthase that
CC polymerize the backbones of noncellulosic polysaccharides
CC (hemicelluloses) of plant cell wall.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi-
CC pass membrane protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in young seedlings, primarily in the
CC vascular tissue. {ECO:0000269|PubMed:11554468}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. Plant
CC cellulose synthase-like B subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC25935.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AC004681; AAC25935.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002685; AEC08697.1; -; Genomic_DNA.
DR EMBL; AY090243; AAL90907.1; -; mRNA.
DR EMBL; BT002290; AAN72301.1; -; mRNA.
DR PIR; T02552; T02552.
DR RefSeq; NP_850190.1; NM_179859.4.
DR AlphaFoldDB; Q8RX83; -.
DR SMR; Q8RX83; -.
DR STRING; 3702.AT2G32530.1; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR iPTMnet; Q8RX83; -.
DR PaxDb; Q8RX83; -.
DR PRIDE; Q8RX83; -.
DR ProteomicsDB; 220502; -.
DR EnsemblPlants; AT2G32530.1; AT2G32530.1; AT2G32530.
DR GeneID; 817814; -.
DR Gramene; AT2G32530.1; AT2G32530.1; AT2G32530.
DR KEGG; ath:AT2G32530; -.
DR Araport; AT2G32530; -.
DR TAIR; locus:2060263; AT2G32530.
DR eggNOG; ENOG502QTT0; Eukaryota.
DR HOGENOM; CLU_001418_3_3_1; -.
DR InParanoid; Q8RX83; -.
DR OMA; ENEVPHF; -.
DR OrthoDB; 267925at2759; -.
DR PhylomeDB; Q8RX83; -.
DR BioCyc; ARA:AT2G32530-MON; -.
DR PRO; PR:Q8RX83; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8RX83; baseline and differential.
DR Genevisible; Q8RX83; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:TAIR.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0016760; F:cellulose synthase (UDP-forming) activity; IEA:InterPro.
DR GO; GO:0051753; F:mannan synthase activity; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:InterPro.
DR GO; GO:0009833; P:plant-type primary cell wall biogenesis; IBA:GO_Central.
DR Gene3D; 3.90.550.10; -; 1.
DR InterPro; IPR005150; Cellulose_synth.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF03552; Cellulose_synt; 2.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 2: Evidence at transcript level;
KW Cell wall biogenesis/degradation; Glycosyltransferase; Golgi apparatus;
KW Membrane; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..755
FT /note="Cellulose synthase-like protein B3"
FT /id="PRO_0000319337"
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 534..556
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 569..589
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 615..635
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 674..694
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 702..722
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 733..753
FT /note="Helical"
FT /evidence="ECO:0000255"
FT ACT_SITE 136
FT /evidence="ECO:0000255"
FT ACT_SITE 461
FT /evidence="ECO:0000255"
SQ SEQUENCE 755 AA; 84889 MW; AC36800B388CF348 CRC64;
MADSSSSLPP LCEKISYKNY FLRVVDLTIL GFLFSLLLYR ILLMNQNNSV WVVAFLCESF
FSFIWLLITS IKWSPASYKS YPERLDERVH DLPSVDMFVT TADPVREPPI LVANTLLSLL
AVNYPANKLA CYVSDDGCSP LTYFSLKEAS KFAKIWVPFC KKYNIKVRAP FRYFLNPPAA
TESSEFSKDW EITKREYEKL SRRVEDATGD SHWLDAEDDF EDFSNTKPND HSTIVKVVWE
NKGGVGVENE VPHFVYISRE KRPNYLHHYK AGAMNFLVRV SGLMTNAPYM LNVDCDMYAN
EADVVRQAMC IFLQKSMNSN HCAFVQFPQE FYDSNADELT VLQSYLGRGI AGIQGPTYAG
SGCFHTRRVM YGLSIDDLED DGSLSSLATR KYLAEENLAR EFGNSNEMVT SVVEALQRKP
NPQNTLANSL EAAQEVGHCH FEYQTSWGKT IGWLYESTAE DANTSIGIHS RGWTSSYISP
KPPAFLGAMP PGGPEAMLQQ RRWATGLLEV LFNKQSPLIG MFCRKIRFRQ SLAYLYIFTW
GLRSIPELIY CLLPAYCLLH NAALFPKGVY LGIVVTLVGM HCLYSLWEFM SLGFSVQSWF
ASQSFWRIKT TCSWLFSIPD IILKLLGISK TVFIVTKKTM PKTMSGSGSE KSQREVDCPN
QDSGKFEFDG SLYFLPGTFI LLVNLAALAG CSVGLQRHRG GGSGLAEACG CILVVILFLP
FLKGMFEKGK YGIPWSTLSK AAFLAVLFVV FSVGN
