CSLB4_ARATH
ID CSLB4_ARATH Reviewed; 755 AA.
AC O80891;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Cellulose synthase-like protein B4;
DE Short=AtCslB4;
DE EC=2.4.1.-;
GN Name=CSLB4; OrderedLocusNames=At2g32540; ORFNames=T26B15.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11027699; DOI=10.1104/pp.124.2.495;
RA Richmond T.A., Somerville C.R.;
RT "The cellulose synthase superfamily.";
RL Plant Physiol. 124:495-498(2000).
CC -!- FUNCTION: Thought to be a Golgi-localized beta-glycan synthase that
CC polymerize the backbones of noncellulosic polysaccharides
CC (hemicelluloses) of plant cell wall.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi-
CC pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. Plant
CC cellulose synthase-like B subfamily. {ECO:0000305}.
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DR EMBL; AC004681; AAC25936.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08698.1; -; Genomic_DNA.
DR PIR; T02553; T02553.
DR RefSeq; NP_180813.1; NM_128813.2.
DR AlphaFoldDB; O80891; -.
DR SMR; O80891; -.
DR STRING; 3702.AT2G32540.1; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR PaxDb; O80891; -.
DR PRIDE; O80891; -.
DR ProteomicsDB; 222662; -.
DR EnsemblPlants; AT2G32540.1; AT2G32540.1; AT2G32540.
DR GeneID; 817815; -.
DR Gramene; AT2G32540.1; AT2G32540.1; AT2G32540.
DR KEGG; ath:AT2G32540; -.
DR Araport; AT2G32540; -.
DR TAIR; locus:2060211; AT2G32540.
DR eggNOG; ENOG502QTT0; Eukaryota.
DR HOGENOM; CLU_001418_3_3_1; -.
DR InParanoid; O80891; -.
DR OMA; GWKSAYC; -.
DR OrthoDB; 267925at2759; -.
DR PhylomeDB; O80891; -.
DR BioCyc; ARA:AT2G32540-MON; -.
DR PRO; PR:O80891; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80891; baseline and differential.
DR Genevisible; O80891; AT.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0016760; F:cellulose synthase (UDP-forming) activity; IEA:InterPro.
DR GO; GO:0051753; F:mannan synthase activity; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:InterPro.
DR GO; GO:0009833; P:plant-type primary cell wall biogenesis; IBA:GO_Central.
DR Gene3D; 3.90.550.10; -; 1.
DR InterPro; IPR005150; Cellulose_synth.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF03552; Cellulose_synt; 2.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 3: Inferred from homology;
KW Cell wall biogenesis/degradation; Glycosyltransferase; Golgi apparatus;
KW Membrane; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..755
FT /note="Cellulose synthase-like protein B4"
FT /id="PRO_0000319338"
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 533..556
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 569..589
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 615..635
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 674..694
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 702..722
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 733..753
FT /note="Helical"
FT /evidence="ECO:0000255"
FT ACT_SITE 136
FT /evidence="ECO:0000255"
FT ACT_SITE 461
FT /evidence="ECO:0000255"
SQ SEQUENCE 755 AA; 84986 MW; 9C8FDB444C77EAD4 CRC64;
MAESSSPLPP LCERISHKSY FLRAVDLTIL GLLLSLLLYR ILHVNQKDTV WIVAFLCETC
FTFVWLLITN IKWSPADYKT YPERLDERVH ELPPVDMFVT TADPVREPPL IVVNTVLSLL
AVNYPANKLA CYVSDDGCSP LTYFSLKEAS KFAKIWVPFC KKYNVRVRAP FMYFRNSPEA
AEGSEFSKDW EMTKREYEKL SQKVEDATGS SHWLDAEDDF EAFLNTKSND HSTIVKVVWE
NKGGVGDEKE VPHVVYISRE KRPNHFHHYK AGAMNFLVRV SGLMTNAPYM LNVDCDMYVN
EADVVRQAMC IFLQKSMDSN HCAFVQYPQD FYDSNVGELT VLQLYLGRGI AGIQGPQYAG
SGCFHTRRVM YGLSLDDLGD DGSLSSIATR KYLAEESLTR EFGNSKEMVK SVVDALQRKP
FPQKNLKDSL ETAQEMGHCH YEYQTSWGKN IGWLYDSTTE DVNTSIGIHS RGWTSSYIFP
DPPAFLGCMP QGGPEVMVQQ RRWATGLLEI LFNKQSPLIG MFCRKIRFRQ SLAYLYVFSW
GLRSIPELFY CLLPAYCLLH NSALFPKGVY LGIIITLVGI HCLYTLWEFM NLGFSIQSWY
VTQSFGRIKT TCSWLFSVLD VILKLLGISK TVFIVTKKTM PETKSGSGSK KSQREVDCPN
QDSGKFEFDG SLYFLPGTFI VLVNLAALAG CLVGLQSRGG GGSGLAEACG CILVVILFLP
FLKGMFEKGK YGIPFSTLSK AAFLAALFVV LSVGN
