CSLD1_ARATH
ID CSLD1_ARATH Reviewed; 1036 AA.
AC O49323; Q680J9;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Cellulose synthase-like protein D1;
DE Short=AtCslD1;
DE EC=2.4.1.-;
GN Name=CSLD1; OrderedLocusNames=At2g33100; ORFNames=F25I18.16;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 216-1036.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11027699; DOI=10.1104/pp.124.2.495;
RA Richmond T.A., Somerville C.R.;
RT "The cellulose synthase superfamily.";
RL Plant Physiol. 124:495-498(2000).
CC -!- FUNCTION: Thought to be a Golgi-localized beta-glycan synthase that
CC polymerize the backbones of noncellulosic polysaccharides
CC (hemicelluloses) of plant cell wall.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi-
CC pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. Plant
CC cellulose synthase-like D subfamily. {ECO:0000305}.
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DR EMBL; AC002334; AAC04910.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08785.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM62806.1; -; Genomic_DNA.
DR EMBL; AK175868; BAD43631.1; -; mRNA.
DR PIR; D84741; D84741.
DR RefSeq; NP_001324935.1; NM_001336422.1.
DR RefSeq; NP_180869.1; NM_128870.4.
DR AlphaFoldDB; O49323; -.
DR SMR; O49323; -.
DR STRING; 3702.AT2G33100.1; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR iPTMnet; O49323; -.
DR SwissPalm; O49323; -.
DR PaxDb; O49323; -.
DR PRIDE; O49323; -.
DR ProteomicsDB; 224538; -.
DR EnsemblPlants; AT2G33100.1; AT2G33100.1; AT2G33100.
DR EnsemblPlants; AT2G33100.2; AT2G33100.2; AT2G33100.
DR GeneID; 817872; -.
DR Gramene; AT2G33100.1; AT2G33100.1; AT2G33100.
DR Gramene; AT2G33100.2; AT2G33100.2; AT2G33100.
DR KEGG; ath:AT2G33100; -.
DR Araport; AT2G33100; -.
DR TAIR; locus:2046505; AT2G33100.
DR eggNOG; ENOG502QQH4; Eukaryota.
DR HOGENOM; CLU_001418_3_1_1; -.
DR InParanoid; O49323; -.
DR OMA; MGHPDEK; -.
DR OrthoDB; 679241at2759; -.
DR PhylomeDB; O49323; -.
DR BioCyc; ARA:AT2G33100-MON; -.
DR PRO; PR:O49323; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O49323; baseline and differential.
DR Genevisible; O49323; AT.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0016760; F:cellulose synthase (UDP-forming) activity; IEA:InterPro.
DR GO; GO:0051753; F:mannan synthase activity; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:InterPro.
DR GO; GO:0009833; P:plant-type primary cell wall biogenesis; IBA:GO_Central.
DR GO; GO:0009846; P:pollen germination; IMP:TAIR.
DR Gene3D; 3.90.550.10; -; 1.
DR InterPro; IPR005150; Cellulose_synth.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF03552; Cellulose_synt; 1.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 2: Evidence at transcript level;
KW Cell wall biogenesis/degradation; Glycosyltransferase; Golgi apparatus;
KW Membrane; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..1036
FT /note="Cellulose synthase-like protein D1"
FT /id="PRO_0000319346"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 817..837
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 848..868
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 895..915
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 938..958
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 962..982
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1002..1022
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 626..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 627..648
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 308
FT /evidence="ECO:0000255"
FT ACT_SITE 741
FT /evidence="ECO:0000255"
FT CONFLICT 996
FT /note="R -> Q (in Ref. 3; BAD43631)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1036 AA; 116067 MW; D1081E4F0527C5F8 CRC64;
MASSPPKKTL NSQSSSLSRP PQAVKFGRRT SSGRIVSLSR DDDMDVSGDY SGQNDYINYT
VLMPPTPDNQ PAGSSGSTSE SKGDANRGGG GGDGPKMGNK LERRLSVMKS NNKSMLLRSQ
TGDFDHNRWL FESKGKYGIG NAFWSEEDDT YDGGVSKSDF LDKPWKPLTR KVQIPAKILS
PYRLLIVIRL VIVFFFLWWR ITNPNEDAMW LWGLSIVCEI WFAFSWILDI LPKLNPINRA
TDLAALHDKF EQPSPSNPTG RSDLPGVDVF VSTADPEKEP PLVTANTLLS ILAVDYPIEK
LSAYISDDGG AILTFEAMAE AVRFAEYWVP FCRKHDIEPR NPDSYFSIKK DPTKNKKRQD
FVKDRRWIKR EYDEFKVRIN GLPEQIKKRA EQFNMREELK EKRIAREKNG GVLPPDGVEV
VKATWMADGT HWPGTWFEPK PDHSKGDHAG ILQIMSKVPD LEPVMGGPNE GALDFTGIDI
RVPMFAYVSR EKRPGFDHNK KAGAMNGMVR ASAILSNGAF ILNLDCDHYI YNSKAIKEGM
CFMMDRGGDR ICYIQFPQRF EGIDPSDRYA NHNTVFFDGN MRALDGLQGP VYVGTGCMFR
RYALYGFNPP RANEYSGVFG QEKAPAMHVR TQSQASQTSQ ASDLESDTQP LNDDPDLGLP
KKFGNSTMFT DTIPVAEYQG RPLADHMSVK NGRPPGALLL PRPPLDAPTV AEAIAVISCW
YEDNTEWGDR IGWIYGSVTE DVVTGYRMHN RGWRSVYCIT KRDAFRGTAP INLTDRLHQV
LRWATGSVEI FFSKNNAMFA TRRLKFLQRV AYLNVGIYPF TSIFLVVYCF LPALCLFSGK
FIVQSLDIHF LSYLLCITVT LTLISLLEVK WSGIGLEEWW RNEQFWLIGG TSAHLAAVVQ
GLLKVIAGIE ISFTLTSKAS GEDEDDIFAD LYIVKWTGLF IMPLTIIIVN LVAIVIGASR
TIYSVIPQWG KLMGGIFFSL WVLTHMYPFA KGLMGRRGKV PTIVYVWSGL VSITVSLLWI
TISPPDDVSG SGGISV
