ID   CSLD2_ORYSJ             Reviewed;        1170 AA.
AC   Q9LHZ7; B7EXX7; Q7PC68; Q8W1N0;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Cellulose synthase-like protein D2;
DE            EC=2.4.1.-;
DE   AltName: Full=OsCslD2;
GN   Name=CSLD2; OrderedLocusNames=Os06g0111800, LOC_Os06g02180;
GN   ORFNames=OsJ_019064, P0029D06.17;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 817-998, AND IDENTIFICATION.
RX   PubMed=11842136; DOI=10.1104/pp.010875;
RA   Hazen S.P., Scott-Craig J.S., Walton J.D.;
RT   "Cellulose synthase-like genes of rice.";
RL   Plant Physiol. 128:336-340(2002).
RN   [7]
RP   TISSUE SPECIFICITY.
RX   PubMed=17259288; DOI=10.1104/pp.106.091546;
RA   Kim C.M., Park S.H., Je B.I., Park S.H., Park S.J., Piao H.L., Eun M.Y.,
RA   Dolan L., Han C.-D.;
RT   "OsCSLD1, a cellulose synthase-like D1 gene, is required for root hair
RT   morphogenesis in rice.";
RL   Plant Physiol. 143:1220-1230(2007).
CC   -!- FUNCTION: Thought to be a Golgi-localized beta-glycan synthase that
CC       polymerize the backbones of noncellulosic polysaccharides
CC       (hemicelluloses) of plant cell wall.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi-
CC       pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. Plant
CC       cellulose synthase-like D subfamily. {ECO:0000305}.
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DR   EMBL; AP001552; BAA93027.1; -; Genomic_DNA.
DR   EMBL; AP008212; BAF18503.1; -; Genomic_DNA.
DR   EMBL; AP014962; BAS95797.1; -; Genomic_DNA.
DR   EMBL; CM000143; EAZ35581.1; -; Genomic_DNA.
DR   EMBL; AK105393; BAG97224.1; -; mRNA.
DR   EMBL; AF435649; AAL38534.1; -; mRNA.
DR   EMBL; BK000900; DAA01753.1; -; Genomic_DNA.
DR   RefSeq; XP_015643356.1; XM_015787870.1.
DR   RefSeq; XP_015643357.1; XM_015787871.1.
DR   AlphaFoldDB; Q9LHZ7; -.
DR   SMR; Q9LHZ7; -.
DR   STRING; 4530.OS06T0111800-02; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   PaxDb; Q9LHZ7; -.
DR   PRIDE; Q9LHZ7; -.
DR   EnsemblPlants; Os06t0111800-01; Os06t0111800-01; Os06g0111800.
DR   EnsemblPlants; Os06t0111800-02; Os06t0111800-02; Os06g0111800.
DR   GeneID; 4339895; -.
DR   Gramene; Os06t0111800-01; Os06t0111800-01; Os06g0111800.
DR   Gramene; Os06t0111800-02; Os06t0111800-02; Os06g0111800.
DR   KEGG; osa:4339895; -.
DR   eggNOG; ENOG502QU14; Eukaryota.
DR   HOGENOM; CLU_001418_1_0_1; -.
DR   InParanoid; Q9LHZ7; -.
DR   OMA; TELMNRP; -.
DR   OrthoDB; 679241at2759; -.
DR   PlantReactome; R-OSA-1119314; Cellulose biosynthesis.
DR   Proteomes; UP000000763; Chromosome 6.
DR   Proteomes; UP000007752; Chromosome 6.
DR   Proteomes; UP000059680; Chromosome 6.
DR   ExpressionAtlas; Q9LHZ7; baseline and differential.
DR   Genevisible; Q9LHZ7; OS.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0016760; F:cellulose synthase (UDP-forming) activity; IEA:InterPro.
DR   GO; GO:0051753; F:mannan synthase activity; IBA:GO_Central.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   GO; GO:0030244; P:cellulose biosynthetic process; IEA:InterPro.
DR   GO; GO:0009833; P:plant-type primary cell wall biogenesis; IBA:GO_Central.
DR   Gene3D; 3.30.40.10; -; 1.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR005150; Cellulose_synth.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   Pfam; PF03552; Cellulose_synt; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   2: Evidence at transcript level;
KW   Cell wall biogenesis/degradation; Coiled coil; Glycosyltransferase;
KW   Golgi apparatus; Membrane; Reference proteome; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..1170
FT                   /note="Cellulose synthase-like protein D2"
FT                   /id="PRO_0000319393"
FT   TRANSMEM        311..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        341..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        955..975
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        981..1001
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1027..1047
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1070..1090
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1104..1124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1134..1154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          54..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          269..295
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          527..551
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..21
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        441
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        873
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1170 AA;  130138 MW;  2BD863A83DB451AF CRC64;
     MASSGGGGLR HSNSSRLSRM SYSGEDGRAQ APGGGGDRPM VTFARRTHSG RYVSYSRDDL
     DSELGNSGDM SPESGQEFLN YHVTIPATPD NQPMDPAISA RVEEQYVSNS LFTGGFNSVT
     RAHLMDKVIE SEASHPQMAG AKGSSCAING CDAKVMSDER GDDILPCECD FKICADCFAD
     AVKNGGACPG CKDPYKATEL DDVVGARPTL SLPPPPGGLP ASRMERRLSI MRSQKAMTRS
     QTGDWDHNRW LFETKGTYGY GNAIWPKENE VDNGGGGGGG GGLGGGDGQP AEFTSKPWRP
     LTRKLKIPAG VLSPYRLLIL IRMAVLGLFL AWRIKHKNED AMWLWGMSVV CELWFGLSWL
     LDQLPKLCPV NRATDLAVLK DKFETPTPSN PNGRSDLPGL DIFVSTADPE KEPPLVTANT
     ILSILAADYP VEKLSCYVSD DGGALLTFEA MAEAASFANM WVPFCRKHDI EPRNPESYFN
     LKRDPYKNKV RSDFVKDRRR VKREYDEFKV RINSLPDSIR RRSDAYHARE EIKAMKRQRE
     AALDDVVEAV KIPKATWMAD GTHWPGTWIQ PSAEHARGDH AGIIQVMLKP PSDDPLYGTS
     GEEGRPLDFT EVDIRLPMLV YVSREKRPGY DHNKKAGAMN ALVRSSAVMS NGPFILNLDC
     DHYVYNSQAF REGMCFMMDR GGDRIGYVQF PQRFEGIDPS DRYANHNTVF FDVNMRALDG
     IMGPVYVGTG CLFRRIALYG FDPPRSKEHS GCCSCCFPQR RKVKTSTVAS EERQALRMAD
     FDDEEMNMSQ FPKKFGNSNF LINSIPIAEF QGRPLADHPG VKNGRPPGAL TVPRDLLDAS
     TVAEAISVIS CWYEDKTEWG QRVGWIYGSV TEDVVTGYRM HNRGWKSVYC VTKRDAFRGT
     APINLTDRLH QVLRWATGSV EIFFSRNNAL LASRKMKFLQ RIAYLNVGIY PFTSIFLIVY
     CFLPALSLFS GQFIVRTLNV TFLTYLLVIT LTMCMLAVLE IKWSGISLEE WWRNEQFWLI
     GGTSAHLAAV LQGLLKVIAG IEISFTLTSK SGGDEADDEF ADLYIVKWTS LMIPPIVIMM
     VNLIAIAVGF SRTIYSEIPQ WSKLLGGVFF SFWVLAHLYP FAKGLMGRRG RTPTIVFVWS
     GLLAITISLL WVAINPPSQN SQIGGSFTFP