CSLE1_ARATH
ID CSLE1_ARATH Reviewed; 729 AA.
AC Q8VZK9; Q56X66; Q9LG28;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Cellulose synthase-like protein E1;
DE Short=AtCslE1;
DE EC=2.4.1.-;
GN Name=CSLE1; OrderedLocusNames=At1g55850; ORFNames=F14J16.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11027699; DOI=10.1104/pp.124.2.495;
RA Richmond T.A., Somerville C.R.;
RT "The cellulose synthase superfamily.";
RL Plant Physiol. 124:495-498(2000).
CC -!- FUNCTION: Thought to be a Golgi-localized beta-glycan synthase that
CC polymerize the backbones of noncellulosic polysaccharides
CC (hemicelluloses) of plant cell wall.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi-
CC pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. Plant
CC cellulose synthase-like E subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79313.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAD93994.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AC002304; AAF79313.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE33308.1; -; Genomic_DNA.
DR EMBL; AY064040; AAL36396.1; -; mRNA.
DR EMBL; AK227116; BAE99166.1; -; mRNA.
DR EMBL; AK221811; BAD93994.1; ALT_INIT; mRNA.
DR RefSeq; NP_175981.2; NM_104462.4.
DR AlphaFoldDB; Q8VZK9; -.
DR SMR; Q8VZK9; -.
DR BioGRID; 27260; 2.
DR STRING; 3702.AT1G55850.1; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR iPTMnet; Q8VZK9; -.
DR SwissPalm; Q8VZK9; -.
DR PaxDb; Q8VZK9; -.
DR PRIDE; Q8VZK9; -.
DR ProteomicsDB; 222619; -.
DR EnsemblPlants; AT1G55850.1; AT1G55850.1; AT1G55850.
DR GeneID; 842035; -.
DR Gramene; AT1G55850.1; AT1G55850.1; AT1G55850.
DR KEGG; ath:AT1G55850; -.
DR Araport; AT1G55850; -.
DR TAIR; locus:2012050; AT1G55850.
DR eggNOG; ENOG502QS7H; Eukaryota.
DR HOGENOM; CLU_001418_3_3_1; -.
DR InParanoid; Q8VZK9; -.
DR OMA; CICLIWF; -.
DR OrthoDB; 679241at2759; -.
DR PhylomeDB; Q8VZK9; -.
DR BioCyc; ARA:AT1G55850-MON; -.
DR PRO; PR:Q8VZK9; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8VZK9; baseline and differential.
DR Genevisible; Q8VZK9; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:TAIR.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0016760; F:cellulose synthase (UDP-forming) activity; IEA:InterPro.
DR GO; GO:0051753; F:mannan synthase activity; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:InterPro.
DR GO; GO:0009833; P:plant-type primary cell wall biogenesis; IBA:GO_Central.
DR Gene3D; 3.90.550.10; -; 2.
DR InterPro; IPR005150; Cellulose_synth.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF03552; Cellulose_synt; 2.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 2: Evidence at transcript level;
KW Cell wall biogenesis/degradation; Glycosyltransferase; Golgi apparatus;
KW Membrane; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..729
FT /note="Cellulose synthase-like protein E1"
FT /id="PRO_0000319352"
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 526..546
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 553..573
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 644..664
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 680..700
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 709..729
FT /note="Helical"
FT /evidence="ECO:0000255"
FT ACT_SITE 152
FT /evidence="ECO:0000255"
FT ACT_SITE 443
FT /evidence="ECO:0000255"
SQ SEQUENCE 729 AA; 82347 MW; A5592FEF88510D1B CRC64;
MVNKDDRIRP VHEADGEPLF ETRRRTGRVI AYRFFSASVF VCICLIWFYR IGEIGDNRTV
LDRLIWFVMF IVEIWFGLYW VVTQSSRWNP VWRFPFSDRL SRRYGSDLPR LDVFVCTADP
VIEPPLLVVN TVLSVTALDY PPEKLAVYLS DDGGSELTFY ALTEAAEFAK TWVPFCKKFN
VEPTSPAAYL SSKANCLDSA AEEVAKLYRE MAARIETAAR LGRIPEEARV KYGDGFSQWD
ADATRRNHGT ILQVLVDGRE GNTIAIPTLV YLSREKRPQH HHNFKAGAMN ALLRVSSKIT
CGKIILNLDC DMYANNSKST RDALCILLDE KEGKEIAFVQ FPQCFDNVTR NDLYGSMMRV
GIDVEFLGLD GNGGPLYIGT GCFHRRDVIC GRKYGEEEEE EESERIHENL EPEMIKALAS
CTYEENTQWG KEMGVKYGCP VEDVITGLTI QCRGWKSAYL NPEKQAFLGV APTNLHQMLV
QQRRWSEGDF QIMLSKYSPV WYGKGKISLG LILGYCCYCL WAPSSLPVLI YSVLTSLCLF
KGIPLFPKVS SSWFIPFGYV TVAATAYSLA EFLWCGGTFR GWWNEQRMWL YRRTSSFLFG
FMDTIKKLLG VSESAFVITA KVAEEEAAER YKEEVMEFGV ESPMFLVLGT LGMLNLFCFA
AAVARLVSGD GGDLKTMGMQ FVITGVLVVI NWPLYKGMLL RQDKGKMPMS VTVKSVVLAL
SACTCLAFL
