CSLG1_ARATH
ID CSLG1_ARATH Reviewed; 760 AA.
AC Q570S7; O22988; Q9T0B4;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Cellulose synthase-like protein G1;
DE Short=AtCslG1;
DE EC=2.4.1.-;
GN Name=CSLG1; OrderedLocusNames=At4g24010; ORFNames=T19F6.17, T32A16.180;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11027699; DOI=10.1104/pp.124.2.495;
RA Richmond T.A., Somerville C.R.;
RT "The cellulose synthase superfamily.";
RL Plant Physiol. 124:495-498(2000).
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=11554468; DOI=10.1023/a:1010627314782;
RA Richmond T.A., Somerville C.R.;
RT "Integrative approaches to determining Csl function.";
RL Plant Mol. Biol. 47:131-143(2001).
CC -!- FUNCTION: Thought to be a Golgi-localized beta-glycan synthase that
CC polymerize the backbones of noncellulosic polysaccharides
CC (hemicelluloses) of plant cell wall.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi-
CC pass membrane protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in young seedlings, primarily in the
CC vascular tissue. {ECO:0000269|PubMed:11554468}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. Plant
CC cellulose synthase-like G subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB63622.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB43901.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB81319.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC002343; AAB63622.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL078468; CAB43901.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161560; CAB81319.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE84839.1; -; Genomic_DNA.
DR EMBL; AK220630; BAD95063.1; -; mRNA.
DR PIR; T08920; T08920.
DR RefSeq; NP_194132.3; NM_118533.4.
DR AlphaFoldDB; Q570S7; -.
DR SMR; Q570S7; -.
DR STRING; 3702.AT4G24010.1; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR PaxDb; Q570S7; -.
DR PRIDE; Q570S7; -.
DR EnsemblPlants; AT4G24010.1; AT4G24010.1; AT4G24010.
DR GeneID; 828501; -.
DR Gramene; AT4G24010.1; AT4G24010.1; AT4G24010.
DR KEGG; ath:AT4G24010; -.
DR Araport; AT4G24010; -.
DR TAIR; locus:2138126; AT4G24010.
DR eggNOG; ENOG502QZE9; Eukaryota.
DR HOGENOM; CLU_001418_3_3_1; -.
DR InParanoid; Q570S7; -.
DR OMA; IYACENK; -.
DR OrthoDB; 679241at2759; -.
DR PhylomeDB; Q570S7; -.
DR BioCyc; ARA:AT4G24010-MON; -.
DR PRO; PR:Q570S7; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q570S7; baseline and differential.
DR Genevisible; Q570S7; AT.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0016760; F:cellulose synthase (UDP-forming) activity; IEA:InterPro.
DR GO; GO:0051753; F:mannan synthase activity; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:InterPro.
DR GO; GO:0009833; P:plant-type primary cell wall biogenesis; IBA:GO_Central.
DR Gene3D; 3.90.550.10; -; 2.
DR InterPro; IPR005150; Cellulose_synth.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF03552; Cellulose_synt; 2.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 2: Evidence at transcript level;
KW Cell wall biogenesis/degradation; Glycosyltransferase; Golgi apparatus;
KW Membrane; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..760
FT /note="Cellulose synthase-like protein G1"
FT /id="PRO_0000319353"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 54..74
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 530..550
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 558..578
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 593..613
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 656..676
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 680..700
FT /note="Helical"
FT /evidence="ECO:0000255"
FT ACT_SITE 142
FT /evidence="ECO:0000255"
FT ACT_SITE 447
FT /evidence="ECO:0000255"
SQ SEQUENCE 760 AA; 86573 MW; 2151766DECCF2A82 CRC64;
METHRKNSVV GNILHTCHPC RRTIPYRIYA IFHTCGIIAL MYHHVHSLVT ANNTLITCLL
LLSDIVLAFM WATTTSLRLN PVHRTECPEK YAAKPEDFPK LDVFICTADP YKEPPMMVVN
TALSVMAYEY PSDKISVYVS DDGGSSLTFF ALIEAAKFSK QWLPFCKKNN VQDRSPEVYF
SSESHSRSDE AENLKMMYED MKSRVEHVVE SGKVETAFIT CDQFRGVFDL WTDKFSRHDH
PTIIQVLQNS ETDMDNTRKY IMPNLIYVSR EKSKVSPHHF KAGALNTLLR VSGVMTNSPI
ILTLDCDMYS NDPATLVRAL CYLTDPEIKS GLGYVQFPQK FLGISKNDIY ACENKRLFII
NMVGFDGLMG PTHVGTGCFF NRRAFYGPPY MLILPEINEL KPYRIADKSI KAQDVLSLAH
NVAGCIYEYN TNWGSKIGFR YGSLVEDYYT GFMLHCEGWR SVFCNPKKAA FYGDSPKCLV
DLVGQQIRWA VGLFEMSFSK YSPITYGIKS LDLLMGLGYC NSPFKPFWSI PLTVYGLLPQ
LALISGVSVF PKASDPWFWL YIILFFGAYA QDLSDFLLEG GTYRKWWNDQ RMLMIKGLSS
FFFGFIEFIL KTLNLSTPKF NVTSKANDDD EQRKRYEQEI FDFGTSSSMF LPLTTVAIVN
LLAFVWGLYG ILFCGGELYL ELMLVSFAVV NCLPIYGAMV LRKDDGKLSK RTCFLAGNLH
VGSYCVKLLR PQVTSPLRLI HNNNTSGWFK RKKHNMNESV
