CSLG3_ARATH
ID CSLG3_ARATH Reviewed; 751 AA.
AC Q0WVN5; O22990; Q9T0B2;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2008, sequence version 2.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Cellulose synthase-like protein G3;
DE Short=AtCslG3;
DE EC=2.4.1.-;
GN Name=CSLG3; OrderedLocusNames=At4g23990; ORFNames=T19F6.19, T32A16.160;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11027699; DOI=10.1104/pp.124.2.495;
RA Richmond T.A., Somerville C.R.;
RT "The cellulose synthase superfamily.";
RL Plant Physiol. 124:495-498(2000).
CC -!- FUNCTION: Thought to be a Golgi-localized beta-glycan synthase that
CC polymerize the backbones of noncellulosic polysaccharides
CC (hemicelluloses) of plant cell wall.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi-
CC pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. Plant
CC cellulose synthase-like G subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB63624.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAE98813.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAB43899.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB81317.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC002343; AAB63624.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL078468; CAB43899.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161560; CAB81317.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE84837.1; -; Genomic_DNA.
DR EMBL; AK226706; BAE98813.1; ALT_INIT; mRNA.
DR PIR; T08918; T08918.
DR RefSeq; NP_194130.3; NM_118531.6.
DR AlphaFoldDB; Q0WVN5; -.
DR SMR; Q0WVN5; -.
DR STRING; 3702.AT4G23990.1; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR PaxDb; Q0WVN5; -.
DR PRIDE; Q0WVN5; -.
DR ProteomicsDB; 224513; -.
DR EnsemblPlants; AT4G23990.1; AT4G23990.1; AT4G23990.
DR GeneID; 828499; -.
DR Gramene; AT4G23990.1; AT4G23990.1; AT4G23990.
DR KEGG; ath:AT4G23990; -.
DR Araport; AT4G23990; -.
DR TAIR; locus:2138106; AT4G23990.
DR eggNOG; ENOG502QZE9; Eukaryota.
DR HOGENOM; CLU_001418_3_3_1; -.
DR InParanoid; Q0WVN5; -.
DR OMA; PLHMSEP; -.
DR OrthoDB; 679241at2759; -.
DR PhylomeDB; Q0WVN5; -.
DR BioCyc; ARA:AT4G23990-MON; -.
DR PRO; PR:Q0WVN5; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q0WVN5; baseline and differential.
DR Genevisible; Q0WVN5; AT.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0016760; F:cellulose synthase (UDP-forming) activity; IEA:InterPro.
DR GO; GO:0051753; F:mannan synthase activity; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:InterPro.
DR GO; GO:0009833; P:plant-type primary cell wall biogenesis; IBA:GO_Central.
DR Gene3D; 3.90.550.10; -; 2.
DR InterPro; IPR005150; Cellulose_synth.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF03552; Cellulose_synt; 2.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 2: Evidence at transcript level;
KW Cell wall biogenesis/degradation; Glycosyltransferase; Golgi apparatus;
KW Membrane; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..751
FT /note="Cellulose synthase-like protein G3"
FT /id="PRO_0000319355"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 543..563
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 577..597
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 617..639
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 674..694
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 697..717
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 731..751
FT /note="Helical"
FT /evidence="ECO:0000255"
FT ACT_SITE 161
FT /evidence="ECO:0000255"
FT ACT_SITE 466
FT /evidence="ECO:0000255"
SQ SEQUENCE 751 AA; 85380 MW; BAFA855C21F6F9F9 CRC64;
MYQVSLKQFV FLLKIKSTTM EPHRKHSVGD TTLHTCHPCR RTIPYRIYAV FHTCGIIALM
YHHVHSLLTA NTTLITSLLL LSDIVLAFMW ATTTSLRYKP VRRTEYPEKY AAEPEDFPKL
DVFICTADPY KEPPMMVVNT ALSVMAYEYP SDKISVYVSD DGGSSLTLFA LMEAAKFSKH
WLPFCKKNNV QDRSPEVYFS SKLRSRSDEA ENIKMMYEDM KSRVEHVVES GKVETAFITC
DQFRGVFDLW TDKFTRHDHP TIIQVLQNSE NDMDDTKKYI MPNLIYVSRE KSKVSSHHFK
AGALNTLLRV SGVMTNSPII LTLDCDMYSN DPATPVRALC YLTDPKIKTG LGFVQFPQTF
QGISKNDIYA CAYKRLFEIN MIGFDGLMGP NHVGTGCFFN RRGFYGAPSN LILPEIDELK
PNRIVDKPIN AQDVLALAHR VAGCIYELNT NWGSKIGFRY GSLVEDYYTG YRLHCEGWRS
VFCRPKRAAF CGDSPKSLID VVSQQKRWAI GLLEVAISRY SPITYGVKSM GLVTGVGYCQ
YACWAFWSLP LIVYGFLPQL ALLYQSSVFP KSSDPWFWLY IVLFLGAYGQ DLLDFVLEGG
TYGGWWNDQR MWSIRGFSSH LFGFIEFTLK TLNLSTHGFN VTSKANDDEE QSKRYEKEIF
EFGPSSSMFL PLTTVAIVNL LAFVWGLYGL FAWGEGLVLE LMLASFAVVN CLPIYEAMVL
RIDDGKLPKR VCFVAGILTF VLIVSGYVFL K
