ID   CSM2_ASHGO              Reviewed;         211 AA.
AC   Q755Z9;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Chromosome segregation in meiosis protein 2;
GN   Name=CSM2; OrderedLocusNames=AER368C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Involved in chromosome segregation during meiosis. Promotes
CC       efficient recombinational repair and functions in the protection of the
CC       genome from spontaneous and induced DNA damage like mutations and gross
CC       chromosomal rearrangements (GCRs) (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CSM2 family. {ECO:0000305}.
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DR   EMBL; AE016818; AAS53048.1; -; Genomic_DNA.
DR   RefSeq; NP_985224.1; NM_210578.1.
DR   AlphaFoldDB; Q755Z9; -.
DR   SMR; Q755Z9; -.
DR   STRING; 33169.AAS53048; -.
DR   EnsemblFungi; AAS53048; AAS53048; AGOS_AER368C.
DR   GeneID; 4621440; -.
DR   KEGG; ago:AGOS_AER368C; -.
DR   eggNOG; ENOG502S2QF; Eukaryota.
DR   HOGENOM; CLU_1235013_0_0_1; -.
DR   InParanoid; Q755Z9; -.
DR   OMA; YIDCKNS; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0097196; C:Shu complex; IEA:InterPro.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0000725; P:recombinational repair; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR031783; Csm2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF16834; CSM2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA repair; Meiosis; Nucleus; Reference proteome.
FT   CHAIN           1..211
FT                   /note="Chromosome segregation in meiosis protein 2"
FT                   /id="PRO_0000280682"
SQ   SEQUENCE   211 AA;  23538 MW;  754713DDE0093BDD CRC64;
     MYIRVLEKLT DTALSAHLIS IYRDYLPTQG TSLPKVVYID CKNSFPIRTF HAHLATAPSA
     LSVTSEQIME NVRVVVCLDL TELRKAIQTL SHSLAVERAS SKETDPSSTS TTFVILCGLD
     AMYRATHLVD HLLAHQQLND SLLRLRILAA EQESGALQTD ILLPRAEFPR AASTLLYKEA
     SNSTHPIKKP RSSWYGSGNM LGDYIIKFYT D