ID   CSM2_CANGA              Reviewed;         214 AA.
AC   Q6FSP5;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Chromosome segregation in meiosis protein 2;
GN   Name=CSM2; OrderedLocusNames=CAGL0G08888g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in chromosome segregation during meiosis. Promotes
CC       efficient recombinational repair and functions in the protection of the
CC       genome from spontaneous and induced DNA damage like mutations and gross
CC       chromosomal rearrangements (GCRs) (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CSM2 family. {ECO:0000305}.
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DR   EMBL; CR380953; CAG59676.1; -; Genomic_DNA.
DR   RefSeq; XP_446749.1; XM_446749.1.
DR   AlphaFoldDB; Q6FSP5; -.
DR   SMR; Q6FSP5; -.
DR   STRING; 5478.XP_446749.1; -.
DR   EnsemblFungi; CAG59676; CAG59676; CAGL0G08888g.
DR   GeneID; 2888359; -.
DR   KEGG; cgr:CAGL0G08888g; -.
DR   CGD; CAL0130013; CAGL0G08888g.
DR   VEuPathDB; FungiDB:CAGL0G08888g; -.
DR   eggNOG; ENOG502S2QF; Eukaryota.
DR   HOGENOM; CLU_108124_0_0_1; -.
DR   InParanoid; Q6FSP5; -.
DR   Proteomes; UP000002428; Chromosome G.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0097196; C:Shu complex; IEA:EnsemblFungi.
DR   GO; GO:0035861; C:site of double-strand break; IEA:EnsemblFungi.
DR   GO; GO:0000730; P:DNA recombinase assembly; IEA:EnsemblFungi.
DR   GO; GO:0043007; P:maintenance of rDNA; IEA:EnsemblFungi.
DR   GO; GO:0045132; P:meiotic chromosome segregation; IEA:EnsemblFungi.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR031783; Csm2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF16834; CSM2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA repair; Meiosis; Nucleus; Reference proteome.
FT   CHAIN           1..214
FT                   /note="Chromosome segregation in meiosis protein 2"
FT                   /id="PRO_0000280683"
SQ   SEQUENCE   214 AA;  24814 MW;  209FC512FAE11CCE CRC64;
     MPPKRYDDLS LLTLWPVAPD IDLAQYIYQF LTSEVGTQTE KEVYFTDSIN SFPIHQLQEL
     VNESNQSIYE NIKINTALDL HELSSIIKKN TESLILKKIQ NKKTNDLKPF QILSVINGLD
     VMFRSTLVSF TNEQAHLMLR DVMLRLRQVC NEYDCSPLTF KIILLFNRSD VMELLPKQRH
     SAAHQQKKMK YNNAMEGNSV GEFVGKYYCD EVAQ