ID   CSMT1_MOUSE             Reviewed;         136 AA.
AC   Q6RUT7;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Protein CCSMST1;
DE   Flags: Precursor;
GN   Name=Ccsmst1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung, Pancreas,
RC   Spleen, and Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CCSMST1 family. {ECO:0000305}.
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DR   EMBL; AY491413; AAS21648.1; -; Genomic_DNA.
DR   CCDS; CCDS57057.1; -.
DR   RefSeq; NP_898973.2; NM_183150.2.
DR   AlphaFoldDB; Q6RUT7; -.
DR   STRING; 10090.ENSMUSP00000137122; -.
DR   iPTMnet; Q6RUT7; -.
DR   PhosphoSitePlus; Q6RUT7; -.
DR   EPD; Q6RUT7; -.
DR   MaxQB; Q6RUT7; -.
DR   PaxDb; Q6RUT7; -.
DR   PeptideAtlas; Q6RUT7; -.
DR   PRIDE; Q6RUT7; -.
DR   ProteomicsDB; 285329; -.
DR   Antibodypedia; 62620; 5 antibodies from 4 providers.
DR   Ensembl; ENSMUST00000088307; ENSMUSP00000137122; ENSMUSG00000067722.
DR   GeneID; 214489; -.
DR   KEGG; mmu:214489; -.
DR   UCSC; uc012amz.1; mouse.
DR   MGI; MGI:2670966; BC003965.
DR   VEuPathDB; HostDB:ENSMUSG00000067722; -.
DR   eggNOG; ENOG502S8XX; Eukaryota.
DR   GeneTree; ENSGT00510000049652; -.
DR   HOGENOM; CLU_142479_1_0_1; -.
DR   InParanoid; Q6RUT7; -.
DR   OMA; LIIWCYL; -.
DR   OrthoDB; 1625962at2759; -.
DR   PhylomeDB; Q6RUT7; -.
DR   TreeFam; TF343850; -.
DR   BioGRID-ORCS; 214489; 2 hits in 74 CRISPR screens.
DR   ChiTaRS; BC003965; mouse.
DR   PRO; PR:Q6RUT7; -.
DR   Proteomes; UP000000589; Chromosome 17.
DR   RNAct; Q6RUT7; protein.
DR   Bgee; ENSMUSG00000067722; Expressed in metanephric renal vesicle and 243 other tissues.
DR   Genevisible; Q6RUT7; MM.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR023248; CCSMST1.
DR   InterPro; IPR029160; CCSMST1_fam.
DR   PANTHER; PTHR35268; PTHR35268; 1.
DR   Pfam; PF15013; CCSMST1; 1.
DR   PRINTS; PR02042; CCSMST1.
PE   1: Evidence at protein level;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000255"
FT   CHAIN           16..136
FT                   /note="Protein CCSMST1"
FT                   /id="PRO_0000348603"
FT   TOPO_DOM        16..80
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        98..136
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          26..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          112..136
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   136 AA;  15348 MW;  5B823F24CEE69223 CRC64;
     MNSVLCSRAA GAVRALRLVG WASRSLHPPP RGRSPAQPAD REEEDDDPNL PIQFSGSKAT
     PIRWTVEHSL GKPQQRPWWK VLPLTLTLVA LVVWCYQREE SGMDLWLRQV LEEEDEEEPE
     GPPEELEAPA LYGART