ID   CSN12_CRYNJ             Reviewed;         403 AA.
AC   P0CR48; Q55KP8; Q5KAS8;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   03-AUG-2022, entry version 40.
DE   RecName: Full=Protein CSN12 homolog;
GN   Name=CSN12; OrderedLocusNames=CNJ00640;
OS   Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS   MYA-565) (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=214684;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEC21 / ATCC MYA-565;
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA   Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA   Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA   Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA   Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA   Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA   Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA   Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT   neoformans.";
RL   Science 307:1321-1324(2005).
CC   -!- SIMILARITY: Belongs to the CSN12 family. {ECO:0000305}.
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DR   EMBL; AE017350; AAW45800.1; -; Genomic_DNA.
DR   RefSeq; XP_567317.1; XM_567317.1.
DR   AlphaFoldDB; P0CR48; -.
DR   SMR; P0CR48; -.
DR   STRING; 5207.AAW45800; -.
DR   PaxDb; P0CR48; -.
DR   EnsemblFungi; AAW45800; AAW45800; CNJ00640.
DR   GeneID; 3254235; -.
DR   KEGG; cne:CNJ00640; -.
DR   VEuPathDB; FungiDB:CNJ00640; -.
DR   eggNOG; KOG2688; Eukaryota.
DR   HOGENOM; CLU_031567_2_1_1; -.
DR   InParanoid; P0CR48; -.
DR   OMA; TYLIPCH; -.
DR   OrthoDB; 706700at2759; -.
DR   Proteomes; UP000002149; Chromosome 10.
DR   GO; GO:0070390; C:transcription export complex 2; IBA:GO_Central.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IBA:GO_Central.
DR   GO; GO:0000973; P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery; IBA:GO_Central.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR045114; Csn12-like.
DR   InterPro; IPR000717; PCI_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR12732; PTHR12732; 1.
DR   Pfam; PF01399; PCI; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..403
FT                   /note="Protein CSN12 homolog"
FT                   /id="PRO_0000121039"
FT   DOMAIN          211..394
FT                   /note="PCI"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
SQ   SEQUENCE   403 AA;  46194 MW;  2B993C012289F0FF CRC64;
     MKYQQFVNSF THPLQHEDHT PLLRLLSVHG KAAKGIADTV GAIDEKRLKN PGHTLPDLWD
     EIAVRHCACV YALYKTKDYT EAFNQQDKLL SLFYRWFVDQ SSWVLPVLYM MLSDLRDLAE
     QADQTIHAET GKMPSLEICT RTVSKAFSLC ATDRQFKGEE SRRRGVYHTA CLTIKCYFKV
     GKPNLCKNII RAVVSDPKTP SVDTAPLPDQ VTWHFYIGML AFLNGEDKKA DEELSWALKH
     CPADAKRNQE LILTYLIPLR LLHGRFPSAS LLSQHPRLEL VFTPFINAIK NGDVEEYDRR
     LEWAQVRLVG MSVWLVVERA REGCLRSLFK KAWMASDKST RVPIETFRLA LKLHGVDVES
     DEVECMVANM IYRGYLKGYI SHEKKMVVLG KTNPFPKMST IAR