ID   CSN12_SCHPO             Reviewed;         423 AA.
AC   O13873;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Protein CSN12 homolog;
GN   Name=csn12; ORFNames=SPAC1B3.08;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- SIMILARITY: Belongs to the CSN12 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU329670; CAB11237.1; -; Genomic_DNA.
DR   PIR; T38026; T38026.
DR   RefSeq; NP_594792.1; NM_001020220.2.
DR   AlphaFoldDB; O13873; -.
DR   SMR; O13873; -.
DR   BioGRID; 278986; 33.
DR   STRING; 4896.SPAC1B3.08.1; -.
DR   MaxQB; O13873; -.
DR   PaxDb; O13873; -.
DR   EnsemblFungi; SPAC1B3.08.1; SPAC1B3.08.1:pep; SPAC1B3.08.
DR   GeneID; 2542528; -.
DR   KEGG; spo:SPAC1B3.08; -.
DR   PomBase; SPAC1B3.08; -.
DR   VEuPathDB; FungiDB:SPAC1B3.08; -.
DR   eggNOG; KOG2688; Eukaryota.
DR   HOGENOM; CLU_031567_2_1_1; -.
DR   InParanoid; O13873; -.
DR   OMA; TYLIPCH; -.
DR   PhylomeDB; O13873; -.
DR   PRO; PR:O13873; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0070390; C:transcription export complex 2; IBA:GO_Central.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IBA:GO_Central.
DR   GO; GO:0000973; P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery; IBA:GO_Central.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR045114; Csn12-like.
DR   InterPro; IPR000717; PCI_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR12732; PTHR12732; 1.
DR   Pfam; PF01399; PCI; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..423
FT                   /note="Protein CSN12 homolog"
FT                   /id="PRO_0000121044"
FT   DOMAIN          232..416
FT                   /note="PCI"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
SQ   SEQUENCE   423 AA;  48044 MW;  5B4414F98EB56E3F CRC64;
     MSERPLPLNV YFSTINSAVA RSNSVLLAKN LSIPWGKTLT SVLNFDIPGT YSSDDVLKLT
     VERSISKNWT DIVLLHLQVL LYLVRDHDPA AAFKQQTELA QHLYREFSSG RCTGVHLPVL
     FIVCKDLRFL AINAHNAMLR RKQQLKVISV DESEENEQLE ATARLINRAF TICINDRAPL
     STSRKWGAYY IMGLLFKLYL RLDCVHLTNN VLRAMKVVEL PDISLFPKSH VVIFHYYLGI
     VAFLNQNYKN ASAELEIAFS LCHKGYNRNL ELILSYWIPT RILVNHQLPT KNLLSKFPNL
     ASVYIPLTRA LKSGNLGEFG KCLQKNETLL AKTKIYLTLE GTRDLCIRNL FRKTWIICGK
     STRLPVSVFQ IALQVAGTDL PKLHVEAILA NMISKGYMRG YISRNFETVV LSAKDPFPKN
     VST