ID   3001L_ASFWA             Reviewed;         268 AA.
AC   P0C9K4;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 25.
DE   RecName: Full=Protein MGF 300-1L;
GN   OrderedLocusNames=War-025;
OS   African swine fever virus (isolate Warthog/Namibia/Wart80/1980) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=561444;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 300 family. {ECO:0000305}.
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DR   EMBL; AY261366; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Proteomes; UP000000858; Genome.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Early protein; Host membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..268
FT                   /note="Protein MGF 300-1L"
FT                   /id="PRO_0000373227"
FT   TOPO_DOM        1..175
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        194..268
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   268 AA;  31345 MW;  650038A7079F3B34 CRC64;
     MVSLTTCCLK NIVNQHAHVE NTVLLYHLGL RWNCKTLYQC TQCNGINYTN SHSDQCKNKD
     LFLMKVIVKK NLAVARTLLS WGASPEYARL FCRNTEEEQA LNVQHVADMS SSKILERLTM
     SYKENDEQLL ITFYLLNLST NFSTNLREQV RFNIVSYIIC DLAIHQTFKT FYAKNYSLST
     LYCIFLAIYY KLYTALRKMV KIYPGLKPFV YLTGFIFDDE TVMETYNSTD DEISECKNRI
     IAIKGCYGNF HCRSDIDHMY AFSQNDYW