ID   CSN4_BRAOL              Reviewed;          45 AA.
AC   P68359;
DT   23-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=COP9 signalosome complex subunit 4;
DE            Short=Signalosome subunit 4;
DE   AltName: Full=Constitutive photomorphogenesis protein 8;
DE   AltName: Full=FUSCA protein 4;
DE            Short=FUSCA4;
DE   Flags: Fragments;
GN   Name=CSN4; Synonyms=COP8, FUS4;
OS   Brassica oleracea (Wild cabbage).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX   NCBI_TaxID=3712;
RN   [1]
RP   PROTEIN SEQUENCE, AND COMPONENT OF THE CSN COMPLEX WITH CSN1; CSN2; CSN3;
RP   CSN5; CSN6; CSN7 AND CSN8.
RX   PubMed=10521526; DOI=10.2307/3871091;
RA   Serino G., Tsuge T., Kwok S., Matsui M., Wei N., Deng X.-W.;
RT   "Arabidopsis cop8 and fus4 mutations define the same gene that encodes
RT   subunit 4 of the COP9 signalosome.";
RL   Plant Cell 11:1967-1980(1999).
CC   -!- FUNCTION: Component of the COP9 signalosome complex (CSN), a complex
CC       involved in various cellular and developmental processes such as
CC       photomorphogenesis and auxin and jasmonate responses. The CSN complex
CC       is an essential regulator of the ubiquitin (Ubl) conjugation pathway by
CC       mediating the deneddylation of the cullin subunits of SCF-type E3
CC       ligase complexes, leading to decrease the Ubl ligase activity of SCF.
CC       It is involved in repression of photomorphogenesis in darkness by
CC       regulating the activity of COP1-containing Ubl ligase complexes (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the CSN complex, probably composed of CSN1, CSN2,
CC       CSN3, CSN4, CSN5 (CSN5A or CSN5B), CSN6 (CSN6A or CSN6B), CSN7 and
CC       CSN8.
CC   -!- INTERACTION:
CC       P68359; P68353: CSN2; NbExp=2; IntAct=EBI-530932, EBI-530927;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
CC   -!- SIMILARITY: Belongs to the CSN4 family. {ECO:0000305}.
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DR   AlphaFoldDB; P68359; -.
DR   IntAct; P68359; 5.
DR   GO; GO:0008180; C:COP9 signalosome; IEA:UniProtKB-KW.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Cytoplasm; Developmental protein; Direct protein sequencing; Nucleus;
KW   Phytochrome signaling pathway; Signalosome.
FT   CHAIN           <1..>45
FT                   /note="COP9 signalosome complex subunit 4"
FT                   /id="PRO_0000120994"
FT   NON_CONS        19..20
FT                   /evidence="ECO:0000305"
FT   NON_TER         1
FT   NON_TER         45
SQ   SEQUENCE   45 AA;  5227 MW;  B29A75E629404959 CRC64;
     KRKFLDAALR YYSISQIEKK AYLPDKSTVL DRAMIEHNNL LSASK