CSN7_BRAOL
ID CSN7_BRAOL Reviewed; 71 AA.
AC P68395;
DT 23-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 25-MAY-2022, entry version 41.
DE RecName: Full=COP9 signalosome complex subunit 7;
DE Short=CSN complex subunit 7;
DE AltName: Full=FUSCA protein 5;
DE Short=FUSCA5;
DE Flags: Fragments;
GN Name=CSN7; Synonyms=FUS5;
OS Brassica oleracea (Wild cabbage).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3712;
RN [1]
RP PROTEIN SEQUENCE OF 1-49.
RX PubMed=9849901; DOI=10.1016/s0014-5793(98)01367-2;
RA Karniol B., Yahalom A., Kwok S., Tsuge T., Matsui M., Deng X.-W.,
RA Chamovitz D.A.;
RT "The Arabidopsis homologue of an eIF3 complex subunit associates with the
RT COP9 complex.";
RL FEBS Lett. 439:173-179(1998).
RN [2]
RP PROTEIN SEQUENCE OF 50-71, AND COMPONENT OF THE CSN COMPLEX WITH CSN1;
RP CSN2; CSN3; CSN4; CSN5; CSN6 AND CSN8.
RX PubMed=10521526; DOI=10.2307/3871091;
RA Serino G., Tsuge T., Kwok S., Matsui M., Wei N., Deng X.-W.;
RT "Arabidopsis cop8 and fus4 mutations define the same gene that encodes
RT subunit 4 of the COP9 signalosome.";
RL Plant Cell 11:1967-1980(1999).
CC -!- FUNCTION: Component of the COP9 signalosome complex (CSN), a complex
CC involved in various cellular and developmental processes such as
CC photomorphogenesis and auxin and jasmonate responses. The CSN complex
CC is an essential regulator of the ubiquitin (Ubl) conjugation pathway by
CC mediating the deneddylation of the cullin subunits of SCF-type E3
CC ligase complexes, leading to decrease the Ubl ligase activity of SCF.
CC It is involved in repression of photomorphogenesis in darkness by
CC regulating the activity of COP1-containing Ubl ligase complexes (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Component of the CSN complex, probably composed of CSN1, CSN2,
CC CSN3, CSN4, CSN5 (CSN5A or CSN5B), CSN6 (CSN6A or CSN6B), CSN7 and
CC CSN8.
CC -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
CC -!- PTM: Phosphorylated. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
CC {ECO:0000305}.
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DR AlphaFoldDB; P68395; -.
DR SMR; P68395; -.
DR IntAct; P68395; 2.
DR GO; GO:0008180; C:COP9 signalosome; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.
DR InterPro; IPR045237; COPS7/eIF3m.
DR PANTHER; PTHR15350; PTHR15350; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Developmental protein; Direct protein sequencing; Nucleus;
KW Phosphoprotein; Phytochrome signaling pathway; Signalosome.
FT CHAIN <1..>71
FT /note="COP9 signalosome complex subunit 7"
FT /id="PRO_0000121004"
FT NON_CONS 9..10
FT /evidence="ECO:0000305"
FT NON_CONS 35..36
FT /evidence="ECO:0000305"
FT NON_CONS 49..50
FT /evidence="ECO:0000305"
FT NON_CONS 60..61
FT /evidence="ECO:0000305"
FT NON_TER 1
FT NON_TER 71
SQ SEQUENCE 71 AA; 8085 MW; 44BCF8AE033D1A4F CRC64;
QAEIIDQLVR LFAHGTWGDY KCNASRIPQL SPDQILKQLT VLTLAESNKK WADNMSEIDK
KEAEEGVEEL K