ID   CSN7_SCHPO              Reviewed;         205 AA.
AC   Q9UUJ7;
DT   29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=COP9 signalosome complex subunit 7;
GN   Name=csn71; Synonyms=csn7a; ORFNames=SPAC1952.12c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-183, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- FUNCTION: Component of the COP9 signalosome (CSN) complex that acts as
CC       an regulator of the ubiquitin (Ubl) conjugation pathway by mediating
CC       the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-
CC       protein ligase complexes. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the COP9 signalosome (CSN) complex.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; CU329670; CAB52576.1; -; Genomic_DNA.
DR   PIR; T37940; T37940.
DR   RefSeq; NP_594814.1; NM_001020243.2.
DR   AlphaFoldDB; Q9UUJ7; -.
DR   SMR; Q9UUJ7; -.
DR   BioGRID; 278603; 31.
DR   STRING; 4896.SPAC1952.12c.1; -.
DR   iPTMnet; Q9UUJ7; -.
DR   PaxDb; Q9UUJ7; -.
DR   PRIDE; Q9UUJ7; -.
DR   EnsemblFungi; SPAC1952.12c.1; SPAC1952.12c.1:pep; SPAC1952.12c.
DR   GeneID; 2542127; -.
DR   KEGG; spo:SPAC1952.12c; -.
DR   PomBase; SPAC1952.12c; csn71.
DR   VEuPathDB; FungiDB:SPAC1952.12c; -.
DR   eggNOG; KOG3250; Eukaryota.
DR   HOGENOM; CLU_1338200_0_0_1; -.
DR   InParanoid; Q9UUJ7; -.
DR   OMA; VSWAMER; -.
DR   PhylomeDB; Q9UUJ7; -.
DR   Reactome; R-SPO-6781823; Formation of TC-NER Pre-Incision Complex.
DR   PRO; PR:Q9UUJ7; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0008180; C:COP9 signalosome; ISO:PomBase.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0000338; P:protein deneddylation; TAS:PomBase.
DR   InterPro; IPR045237; COPS7/eIF3m.
DR   InterPro; IPR000717; PCI_dom.
DR   PANTHER; PTHR15350; PTHR15350; 1.
DR   SMART; SM00088; PINT; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome; Signalosome.
FT   CHAIN           1..205
FT                   /note="COP9 signalosome complex subunit 7"
FT                   /id="PRO_0000121005"
FT   DOMAIN          1..135
FT                   /note="PCI"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
FT   MOD_RES         183
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
SQ   SEQUENCE   205 AA;  23839 MW;  7527640DF8DFF93B CRC64;
     MEEKISQAID DPNVFCFQEL WIECQEVQKS QPIDSAVLRT LEIFCRGDIR DASSEWNELR
     FKKLRLLTLI DLANRHVGSS VSFETILVHL QLDRLPPSDP TFTVEYYIMQ AMMNQILVGK
     INAKTQTLHV SWALERFLDS KRIDEMKYSL DRFIERCSNI LFQLDAGTPS VSKSFKRASR
     MSSSDGIDYM VFDKRPRPDD TDFDL