CSN8_BRAOL
ID CSN8_BRAOL Reviewed; 23 AA.
AC P68396;
DT 23-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 25-MAY-2022, entry version 30.
DE RecName: Full=COP9 signalosome complex subunit 8;
DE Short=CSN complex subunit 8;
DE AltName: Full=Constitutive photomorphogenesis protein 9;
DE AltName: Full=FUSCA protein 7;
DE Short=FUSCA7;
DE Flags: Fragment;
GN Name=CSN8; Synonyms=COP9, FUS7;
OS Brassica oleracea (Wild cabbage).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3712;
RN [1]
RP PROTEIN SEQUENCE, AND COMPOSITION OF THE CSN COMPLEX.
RX PubMed=9849901; DOI=10.1016/s0014-5793(98)01367-2;
RA Karniol B., Yahalom A., Kwok S., Tsuge T., Matsui M., Deng X.-W.,
RA Chamovitz D.A.;
RT "The Arabidopsis homologue of an eIF3 complex subunit associates with the
RT COP9 complex.";
RL FEBS Lett. 439:173-179(1998).
CC -!- FUNCTION: Component of the COP9 signalosome complex (CSN), a complex
CC involved in various cellular and developmental processes such as
CC photomorphogenesis and auxin and jasmonate responses. The CSN complex
CC is an essential regulator of the ubiquitin (Ubl) conjugation pathway by
CC mediating the deneddylation of the cullin subunits of SCF-type E3
CC ligase complexes, leading to decrease the Ubl ligase activity of SCF.
CC It is involved in repression of photomorphogenesis in darkness by
CC regulating the activity of COP1-containing Ubl ligase complexes (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Component of the CSN complex, probably composed of CSN1, CSN2,
CC CSN3, CSN4, CSN5 (CSN5A or CSN5B), CSN6 (CSN6A or CSN6B), CSN7 and
CC CSN8.
CC -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
CC -!- SIMILARITY: Belongs to the CSN8 family. {ECO:0000305}.
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DR AlphaFoldDB; P68396; -.
DR GO; GO:0008180; C:COP9 signalosome; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Cytoplasm; Developmental protein; Direct protein sequencing; Nucleus;
KW Phytochrome signaling pathway; Signalosome.
FT CHAIN <1..>23
FT /note="COP9 signalosome complex subunit 8"
FT /id="PRO_0000121016"
FT NON_TER 1
FT NON_TER 23
SQ SEQUENCE 23 AA; 2748 MW; 0DD270E2E474914A CRC64;
LWTRDYAGVY EAIRGFDWSQ DAK
