ID   CSN9_ASHGO              Reviewed;         163 AA.
AC   Q750S5;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=COP9 signalosome complex subunit 9;
GN   Name=CSN9; OrderedLocusNames=AGL136C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Component of the COP9 signalosome (CSN) complex that acts as
CC       a regulator of the ubiquitin (Ubl) conjugation pathway by mediating the
CC       deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein
CC       ligase complexes. The complex is involved in the regulation of the
CC       mating pheromone response (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of a COP9 signalosome-like (CSN) complex.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
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DR   EMBL; AE016820; AAS54355.1; -; Genomic_DNA.
DR   RefSeq; NP_986531.1; NM_211593.1.
DR   AlphaFoldDB; Q750S5; -.
DR   SMR; Q750S5; -.
DR   STRING; 33169.AAS54355; -.
DR   EnsemblFungi; AAS54355; AAS54355; AGOS_AGL136C.
DR   GeneID; 4622830; -.
DR   KEGG; ago:AGOS_AGL136C; -.
DR   eggNOG; ENOG502S4AD; Eukaryota.
DR   HOGENOM; CLU_138722_0_0_1; -.
DR   InParanoid; Q750S5; -.
DR   OMA; FDCRDVY; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0008180; C:COP9 signalosome; IEA:UniProtKB-KW.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IEA:EnsemblFungi.
DR   GO; GO:0000338; P:protein deneddylation; IEA:EnsemblFungi.
DR   InterPro; IPR016806; Csn9_fungi.
DR   PIRSF; PIRSF022632; UCP022632; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome; Signalosome.
FT   CHAIN           1..163
FT                   /note="COP9 signalosome complex subunit 9"
FT                   /id="PRO_0000121017"
FT   DOMAIN          5..120
FT                   /note="PCI"
SQ   SEQUENCE   163 AA;  18848 MW;  25E7A7107157D043 CRC64;
     MIRQEVLHAV LDPKAVHFKQ FWLSSVDRDE SELLEVLCFG NYGDLNAIQS CEEWKDAIES
     KLRTLTLLGL CEVPSELEYD QAMASCCIPD DVILEQRMVE LQAQVHFQLD SVGRRIKVLR
     CLGARDIYNG ERPLLLLRDA ARSRESTLAG LRQWKQKLQY QLR