ID   CSOA2_ECOLX             Reviewed;         171 AA.
AC   P0ABW8; P25730;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=CS1 fimbrial subunit A;
DE   AltName: Full=CS1 pilin;
DE   Flags: Precursor;
GN   Name=csoA; Synonyms=cooA;
OS   Escherichia coli.
OG   Plasmid pEU605.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=O6:H16 / ETEC;
RX   PubMed=1977705; DOI=10.1128/iai.58.11.3594-3600.1990;
RA   Perez-Casal J., Swartley J.S., Scott J.R.;
RT   "Gene encoding the major subunit of CS1 pili of human enterotoxigenic
RT   Escherichia coli.";
RL   Infect. Immun. 58:3594-3600(1990).
CC   -!- FUNCTION: Fimbriae (also called pili), polar filaments radiating from
CC       the surface of the bacterium to a length of 0.5-1.5 micrometers and
CC       numbering 100-300 per cell, enable bacteria to colonize the epithelium
CC       of specific host organs.
CC   -!- SUBCELLULAR LOCATION: Fimbrium.
CC   -!- INDUCTION: CS1 fimbriae are only expressed in the presence of the
CC       positive regulator rns.
CC   -!- SIMILARITY: Belongs to the fimbrial CS1 protein family. {ECO:0000305}.
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DR   EMBL; M58550; AAA23596.1; -; Genomic_DNA.
DR   PIR; A41467; A41467.
DR   RefSeq; WP_000768757.1; NZ_LRLU01000168.1.
DR   RefSeq; YP_424820.1; NC_007635.1.
DR   AlphaFoldDB; P0ABW8; -.
DR   SMR; P0ABW8; -.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007540; Fimbrial_CS1-type.
DR   Pfam; PF04449; Fimbrial_CS1; 1.
PE   2: Evidence at transcript level;
KW   Fimbrium; Plasmid; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000250"
FT   CHAIN           24..171
FT                   /note="CS1 fimbrial subunit A"
FT                   /id="PRO_0000042686"
SQ   SEQUENCE   171 AA;  17542 MW;  46E70EE7053DBE13 CRC64;
     MKLKKTIGAM ALATLFATMG ASAVEKTISV TASVDPTVDL LQSDGSALPN SVALTYSPAV
     NNFEAHTINT VVHTNDSDKG VVVKLSADPV LSNVLNPTLQ IPVSVNFAGK PLSTTGITID
     SNDLNFASSG VNKVSSTQKL SIHADATRVT GGALTAGQYQ GLVSIILTKS T