ID   CSOS1_PROMP             Reviewed;         103 AA.
AC   Q7V2D1;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 2.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Major carboxysome shell protein CsoS1 {ECO:0000303|PubMed:22155772};
GN   Name=csoS1 {ECO:0000303|PubMed:22155772}; OrderedLocusNames=PMM0549;
OS   Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 /
OS   MED4).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=59919;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1986 / NIES-2087 / MED4;
RX   PubMed=12917642; DOI=10.1038/nature01947;
RA   Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A.,
RA   Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L.,
RA   Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C.,
RA   Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R.,
RA   Chisholm S.W.;
RT   "Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche
RT   differentiation.";
RL   Nature 424:1042-1047(2003).
RN   [2]
RP   PROTEIN ABUNDANCE, AND SUBCELLULAR LOCATION.
RC   STRAIN=CCMP1986 / NIES-2087 / MED4;
RX   PubMed=22155772; DOI=10.1128/jb.06444-11;
RA   Roberts E.W., Cai F., Kerfeld C.A., Cannon G.C., Heinhorst S.;
RT   "Isolation and characterization of the Prochlorococcus carboxysome reveal
RT   the presence of the novel shell protein CsoS1D.";
RL   J. Bacteriol. 194:787-795(2012).
RN   [3]
RP   SUBUNIT.
RC   STRAIN=CCMP1986 / NIES-2087 / MED4;
RX   PubMed=25826651; DOI=10.3390/life5021141;
RA   Cai F., Dou Z., Bernstein S.L., Leverenz R., Williams E.B., Heinhorst S.,
RA   Shively J., Cannon G.C., Kerfeld C.A.;
RT   "Advances in Understanding Carboxysome Assembly in Prochlorococcus and
RT   Synechococcus Implicate CsoS2 as a Critical Component.";
RL   Life 5:1141-1171(2015).
CC   -!- FUNCTION: The major shell protein of the carboxysome, a polyhedral
CC       inclusion where RuBisCO (ribulose bisphosphate carboxylase, ccbL-ccbS)
CC       is sequestered. Assembles into hexamers which make sheets that form the
CC       facets of the polyhedral carboxysome (By similarity). There are
CC       estimated to be 538 CsoS1 hexamers per carboxysome; note this number
CC       includes the probable carboxysome shell vertex proteins CsoS4A and
CC       CsoS4B (PubMed:22155772). {ECO:0000250|UniProtKB:P45689,
CC       ECO:0000269|PubMed:22155772}.
CC   -!- SUBUNIT: Homohexamer with a small central pore (By similarity). A
CC       CsoS1-CsoS1D-CsoS2 complex can be isolated following expression in
CC       E.coli (PubMed:25826651). Forms a CsoS2-CsoS1-RuBisCO complex (By
CC       similarity). {ECO:0000250|UniProtKB:P45689,
CC       ECO:0000269|PubMed:25826651}.
CC   -!- SUBCELLULAR LOCATION: Carboxysome {ECO:0000269|PubMed:22155772}.
CC       Note=This bacterium makes alpha-type carboxysomes.
CC       {ECO:0000269|PubMed:25826651}.
CC   -!- DOMAIN: The tight homohexamer forms a small pore which is positively
CC       charged. {ECO:0000250|UniProtKB:P45689}.
CC   -!- SIMILARITY: Belongs to the bacterial microcompartments protein family.
CC       CsoS1 subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAE19008.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; BX548174; CAE19008.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_011819929.1; NC_005072.1.
DR   AlphaFoldDB; Q7V2D1; -.
DR   SMR; Q7V2D1; -.
DR   STRING; 59919.PMM0549; -.
DR   EnsemblBacteria; CAE19008; CAE19008; PMM0549.
DR   KEGG; pmm:PMM0549; -.
DR   eggNOG; COG4577; Bacteria.
DR   HOGENOM; CLU_064903_5_3_3; -.
DR   OMA; QFREGVN; -.
DR   OrthoDB; 1802372at2; -.
DR   Proteomes; UP000001026; Chromosome.
DR   GO; GO:0031470; C:carboxysome; IEA:UniProtKB-SubCell.
DR   GO; GO:0043886; F:structural constituent of carboxysome; IEA:UniProt.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-KW.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.1710; -; 1.
DR   InterPro; IPR020808; Bact_microcomp_CS.
DR   InterPro; IPR000249; BMC_dom.
DR   InterPro; IPR037233; CcmK-like_sf.
DR   InterPro; IPR044872; CcmK/CsoS1_BMC.
DR   Pfam; PF00936; BMC; 1.
DR   SMART; SM00877; BMC; 1.
DR   SUPFAM; SSF143414; SSF143414; 1.
DR   PROSITE; PS01139; BMC_1; 1.
DR   PROSITE; PS51930; BMC_2; 1.
PE   1: Evidence at protein level;
KW   Bacterial microcompartment; Carbon dioxide fixation; Carboxysome;
KW   Photosynthesis.
FT   CHAIN           1..103
FT                   /note="Major carboxysome shell protein CsoS1"
FT                   /id="PRO_0000201501"
FT   DOMAIN          9..94
FT                   /note="BMC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01278"
SQ   SEQUENCE   103 AA;  10572 MW;  DC707658A5FCCEB7 CRC64;
     MATETMGIAL GMIETRGLVP AIEAADAMTK AAEVRLIGRE FVGGGYVTVL VRGETGAVNA
     AVRAGADACE RVGDGLVAAH IIARPHREVE PALGNGDFLG QKD