ID   CSPA_KLEAK              Reviewed;          70 AA.
AC   Q46664; G0E7T1;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   14-DEC-2011, sequence version 2.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Major cold shock protein;
GN   Name=cspA; OrderedLocusNames=EAE_06080;
OS   Klebsiella aerogenes (strain ATCC 13048 / DSM 30053 / CCUG 1429 / JCM 1235
OS   / KCTC 2190 / NBRC 13534 / NCIMB 10102 / NCTC 10006 / CDC 819-56)
OS   (Enterobacter aerogenes).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=1028307;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13048 / DSM 30053 / CCUG 1429 / JCM 1235 / KCTC 2190 / NBRC
RC   13534 / NCIMB 10102 / NCTC 10006 / CDC 819-56;
RX   PubMed=22493190; DOI=10.1128/jb.00028-12;
RA   Shin S.H., Kim S., Kim J.Y., Lee S., Um Y., Oh M.K., Kim Y.R., Lee J.,
RA   Yang K.S.;
RT   "Complete genome sequence of Enterobacter aerogenes KCTC 2190.";
RL   J. Bacteriol. 194:2373-2374(2012).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 15-60.
RC   STRAIN=ATCC 13048 / DSM 30053 / CCUG 1429 / JCM 1235 / KCTC 2190 / NBRC
RC   13534 / NCIMB 10102 / NCTC 10006 / CDC 819-56;
RX   PubMed=9439003; DOI=10.1038/sj.jim.2900463;
RA   Francis K.P., Stewart G.S.A.B.;
RT   "Detection and speciation of bacteria through PCR using universal major
RT   cold-shock protein primer oligomers.";
RL   J. Ind. Microbiol. Biotechnol. 19:286-293(1997).
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- INDUCTION: In response to low temperature. {ECO:0000250}.
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DR   EMBL; CP002824; AEG96140.1; -; Genomic_DNA.
DR   EMBL; U60034; AAC80238.1; -; Genomic_DNA.
DR   RefSeq; WP_000014594.1; NC_015663.1.
DR   RefSeq; YP_004591419.1; NC_015663.1.
DR   AlphaFoldDB; Q46664; -.
DR   SMR; Q46664; -.
DR   STRING; 1028307.EAE_06080; -.
DR   EnsemblBacteria; AEG96140; AEG96140; EAE_06080.
DR   GeneID; 64293021; -.
DR   GeneID; 67517040; -.
DR   KEGG; eae:EAE_06080; -.
DR   PATRIC; fig|1028307.3.peg.1212; -.
DR   eggNOG; COG1278; Bacteria.
DR   HOGENOM; CLU_117621_2_1_6; -.
DR   OMA; GPCANKV; -.
DR   PRO; PR:Q46664; -.
DR   Proteomes; UP000008881; Chromosome.
DR   GO; GO:0005829; C:cytosol; IEA:UniProt.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd04458; CSP_CDS; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   InterPro; IPR012156; Cold_shock_CspA.
DR   InterPro; IPR011129; CSD.
DR   InterPro; IPR019844; CSD_1.
DR   InterPro; IPR002059; CSP_DNA-bd.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   Pfam; PF00313; CSD; 1.
DR   PIRSF; PIRSF002599; Cold_shock_A; 1.
DR   PRINTS; PR00050; COLDSHOCK.
DR   SMART; SM00357; CSP; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   PROSITE; PS00352; CSD_1; 1.
DR   PROSITE; PS51857; CSD_2; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; DNA-binding; Stress response; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..70
FT                   /note="Major cold shock protein"
FT                   /id="PRO_0000100303"
FT   DOMAIN          4..69
FT                   /note="CSD"
SQ   SEQUENCE   70 AA;  7403 MW;  CED47F00BF18A49B CRC64;
     MSGKMTGIVK WFNADKGFGF ITPDDGSKDV FVHFSAIQND GYKSLDEGQK VSFTIESGAK
     GPAAGNVTSL