ID   CSPA_SALTI              Reviewed;          70 AA.
AC   P0A9Y3; P15277; P37410; Q54170;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Cold shock protein CspA;
DE            Short=CSP-A;
DE   AltName: Full=7.4 kDa cold shock protein;
DE   AltName: Full=CS7.4;
GN   Name=cspA; OrderedLocusNames=STY4153, t3870;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Binds to and stimulates the transcription of the CCAAT-
CC       containing, cold-shock-inducible promoters of the H-NS and GyrA
CC       proteins. Binds also to the inverted repeat 5'-ATTGG-3' (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- INDUCTION: In response to low temperature. {ECO:0000250}.
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DR   EMBL; AL513382; CAD07979.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO71348.1; -; Genomic_DNA.
DR   RefSeq; NP_458276.1; NC_003198.1.
DR   RefSeq; WP_000014594.1; NZ_WSUR01000001.1.
DR   AlphaFoldDB; P0A9Y3; -.
DR   BMRB; P0A9Y3; -.
DR   SMR; P0A9Y3; -.
DR   STRING; 220341.16504965; -.
DR   EnsemblBacteria; AAO71348; AAO71348; t3870.
DR   GeneID; 64293021; -.
DR   GeneID; 67517040; -.
DR   KEGG; stt:t3870; -.
DR   KEGG; sty:STY4153; -.
DR   PATRIC; fig|220341.7.peg.4240; -.
DR   eggNOG; COG1278; Bacteria.
DR   HOGENOM; CLU_117621_2_1_6; -.
DR   OMA; GPCANKV; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0005829; C:cytosol; IEA:UniProt.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd04458; CSP_CDS; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   InterPro; IPR012156; Cold_shock_CspA.
DR   InterPro; IPR011129; CSD.
DR   InterPro; IPR019844; CSD_1.
DR   InterPro; IPR002059; CSP_DNA-bd.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   Pfam; PF00313; CSD; 1.
DR   PIRSF; PIRSF002599; Cold_shock_A; 1.
DR   PRINTS; PR00050; COLDSHOCK.
DR   SMART; SM00357; CSP; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   PROSITE; PS00352; CSD_1; 1.
DR   PROSITE; PS51857; CSD_2; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; DNA-binding; Stress response; Transcription;
KW   Transcription regulation.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..70
FT                   /note="Cold shock protein CspA"
FT                   /id="PRO_0000100237"
FT   DOMAIN          7..67
FT                   /note="CSD"
SQ   SEQUENCE   70 AA;  7403 MW;  CED47F00BF18A49B CRC64;
     MSGKMTGIVK WFNADKGFGF ITPDDGSKDV FVHFSAIQND GYKSLDEGQK VSFTIESGAK
     GPAAGNVTSL