CSPA_STRP3
ID CSPA_STRP3 Reviewed; 67 AA.
AC P0DA48; P0A360; Q54974;
DT 27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 1.
DT 25-MAY-2022, entry version 51.
DE RecName: Full=Major cold shock protein;
GN Name=cspA; Synonyms=csp, cspC; OrderedLocusNames=SpyM3_1769;
OS Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=198466;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-595 / MGAS315;
RX PubMed=12122206; DOI=10.1073/pnas.152298499;
RA Beres S.B., Sylva G.L., Barbian K.D., Lei B., Hoff J.S., Mammarella N.D.,
RA Liu M.-Y., Smoot J.C., Porcella S.F., Parkins L.D., Campbell D.S.,
RA Smith T.M., McCormick J.K., Leung D.Y.M., Schlievert P.M., Musser J.M.;
RT "Genome sequence of a serotype M3 strain of group A Streptococcus: phage-
RT encoded toxins, the high-virulence phenotype, and clone emergence.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:10078-10083(2002).
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- INDUCTION: In response to low temperature. {ECO:0000250}.
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DR EMBL; AE014074; AAM80376.1; -; Genomic_DNA.
DR RefSeq; WP_002991299.1; NC_004070.1.
DR AlphaFoldDB; P0DA48; -.
DR SMR; P0DA48; -.
DR EnsemblBacteria; AAM80376; AAM80376; SpyM3_1769.
DR GeneID; 57853431; -.
DR KEGG; spg:SpyM3_1769; -.
DR HOGENOM; CLU_117621_6_1_9; -.
DR OMA; FEIQDGH; -.
DR Proteomes; UP000000564; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd04458; CSP_CDS; 1.
DR Gene3D; 2.40.50.140; -; 1.
DR InterPro; IPR012156; Cold_shock_CspA.
DR InterPro; IPR011129; CSD.
DR InterPro; IPR019844; CSD_1.
DR InterPro; IPR002059; CSP_DNA-bd.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR Pfam; PF00313; CSD; 1.
DR PIRSF; PIRSF002599; Cold_shock_A; 1.
DR PRINTS; PR00050; COLDSHOCK.
DR SMART; SM00357; CSP; 1.
DR SUPFAM; SSF50249; SSF50249; 1.
DR PROSITE; PS00352; CSD_1; 1.
DR PROSITE; PS51857; CSD_2; 1.
PE 3: Inferred from homology;
KW Activator; Cytoplasm; DNA-binding; Stress response; Transcription;
KW Transcription regulation.
FT CHAIN 1..67
FT /note="Major cold shock protein"
FT /id="PRO_0000100335"
FT DOMAIN 4..63
FT /note="CSD"
SQ SEQUENCE 67 AA; 7322 MW; A8D499734D82C3F0 CRC64;
MAQGTVKWFN AEKGFGFIST ENGQDVFAHF SAIQTNGFKT LEEGQKVAFD VEEGQRGPQA
VNITKLA