ID   CSPA_STRPY              Reviewed;          45 AA.
AC   P0C0F0; P0A359; Q54974;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Major cold shock protein;
DE   Flags: Fragment;
GN   Name=cspA; Synonyms=csp, cspC;
OS   Streptococcus pyogenes.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1314;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=NCTC 8198;
RX   PubMed=9439003; DOI=10.1038/sj.jim.2900463;
RA   Francis K.P., Stewart G.S.A.B.;
RT   "Detection and speciation of bacteria through PCR using universal major
RT   cold-shock protein primer oligomers.";
RL   J. Ind. Microbiol. Biotechnol. 19:286-293(1997).
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- INDUCTION: In response to low temperature. {ECO:0000250}.
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DR   EMBL; U60054; AAC80258.1; -; Genomic_DNA.
DR   AlphaFoldDB; P0C0F0; -.
DR   SMR; P0C0F0; -.
DR   eggNOG; COG1278; Bacteria.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd04458; CSP_CDS; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   InterPro; IPR012156; Cold_shock_CspA.
DR   InterPro; IPR011129; CSD.
DR   InterPro; IPR019844; CSD_1.
DR   InterPro; IPR002059; CSP_DNA-bd.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   Pfam; PF00313; CSD; 1.
DR   PIRSF; PIRSF002599; Cold_shock_A; 1.
DR   PRINTS; PR00050; COLDSHOCK.
DR   SMART; SM00357; CSP; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   PROSITE; PS00352; CSD_1; 1.
DR   PROSITE; PS51857; CSD_2; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; DNA-binding; Stress response; Transcription;
KW   Transcription regulation.
FT   CHAIN           <1..>45
FT                   /note="Major cold shock protein"
FT                   /id="PRO_0000100333"
FT   DOMAIN          <1..>45
FT                   /note="CSD"
FT   NON_TER         1
FT   NON_TER         45
SQ   SEQUENCE   45 AA;  4994 MW;  FCB09CAD272B165F CRC64;
     EKGFGFISTE NGQDVFAHFS AIQTNGFKTL EEGQKVAFDV EEGQR