ID   CSPD_BACSU              Reviewed;          66 AA.
AC   P51777;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=Cold shock protein CspD;
GN   Name=cspD; OrderedLocusNames=BSU21930;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB
RC   3610 / NRRL NRS-744 / VKM B-501;
RX   PubMed=8969496; DOI=10.1099/13500872-142-11-3005;
RA   Capuano V., Galleron N., Pujic P., Sorokin A., Ehrlich S.D.;
RT   "Organization of the Bacillus subtilis 168 chromosome between kdg and the
RT   attachment site of the SP beta prophage: use of long accurate PCR and yeast
RT   artificial chromosomes for sequencing.";
RL   Microbiology 142:3005-3015(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 59-66.
RX   PubMed=3098734; DOI=10.1128/jb.169.1.434-437.1987;
RA   Yang M., Shimotsu H., Ferrari E., Henner D.J.;
RT   "Characterization and mapping of the Bacillus subtilis prtR gene.";
RL   J. Bacteriol. 169:434-437(1987).
RN   [4]
RP   PROTEIN SEQUENCE OF 1-40.
RC   STRAIN=168 / JH642;
RX   PubMed=8755892; DOI=10.1128/jb.178.15.4611-4619.1996;
RA   Graumann P., Schroeder K., Schmid R., Marahiel M.A.;
RT   "Cold shock stress-induced proteins in Bacillus subtilis.";
RL   J. Bacteriol. 178:4611-4619(1996).
RN   [5]
RP   DISRUPTION PHENOTYPE.
RC   STRAIN=168 / JH642;
RX   PubMed=16352840; DOI=10.1128/jb.188.1.240-248.2006;
RA   Hunger K., Beckering C.L., Wiegeshoff F., Graumann P.L., Marahiel M.A.;
RT   "Cold-induced putative DEAD box RNA helicases CshA and CshB are essential
RT   for cold adaptation and interact with cold shock protein B in Bacillus
RT   subtilis.";
RL   J. Bacteriol. 188:240-248(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- INDUCTION: In response to low temperature.
CC   -!- DISRUPTION PHENOTYPE: A double cshB-cspD mutant grows slowly at 15
CC       degrees Celsius. {ECO:0000269|PubMed:16352840}.
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DR   EMBL; L77246; AAA96623.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB14111.1; -; Genomic_DNA.
DR   EMBL; M15318; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; F69608; F69608.
DR   RefSeq; NP_390076.1; NC_000964.3.
DR   RefSeq; WP_003230776.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; P51777; -.
DR   SMR; P51777; -.
DR   STRING; 224308.BSU21930; -.
DR   jPOST; P51777; -.
DR   PaxDb; P51777; -.
DR   PRIDE; P51777; -.
DR   EnsemblBacteria; CAB14111; CAB14111; BSU_21930.
DR   GeneID; 56672019; -.
DR   GeneID; 939079; -.
DR   KEGG; bsu:BSU21930; -.
DR   PATRIC; fig|224308.179.peg.2395; -.
DR   eggNOG; COG1278; Bacteria.
DR   InParanoid; P51777; -.
DR   OMA; TEEIFVH; -.
DR   PhylomeDB; P51777; -.
DR   BioCyc; BSUB:BSU21930-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0001072; F:transcription antitermination factor activity, RNA binding; IBA:GO_Central.
DR   GO; GO:0060567; P:negative regulation of DNA-templated transcription, termination; IBA:GO_Central.
DR   GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR   CDD; cd04458; CSP_CDS; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   InterPro; IPR012156; Cold_shock_CspA.
DR   InterPro; IPR011129; CSD.
DR   InterPro; IPR019844; CSD_1.
DR   InterPro; IPR002059; CSP_DNA-bd.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   Pfam; PF00313; CSD; 1.
DR   PIRSF; PIRSF002599; Cold_shock_A; 1.
DR   PRINTS; PR00050; COLDSHOCK.
DR   SMART; SM00357; CSP; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   PROSITE; PS00352; CSD_1; 1.
DR   PROSITE; PS51857; CSD_2; 1.
PE   1: Evidence at protein level;
KW   Activator; Cytoplasm; Direct protein sequencing; DNA-binding;
KW   Reference proteome; Stress response; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..66
FT                   /note="Cold shock protein CspD"
FT                   /id="PRO_0000100297"
FT   DOMAIN          4..63
FT                   /note="CSD"
SQ   SEQUENCE   66 AA;  7309 MW;  1A6CDA24E3A5AC58 CRC64;
     MQNGKVKWFN NEKGFGFIEV EGGDDVFVHF TAIEGDGYKS LEEGQEVSFE IVEGNRGPQA
     SNVVKL