ID   CSPL1_EUTHA             Reviewed;         199 AA.
AC   E4MWF4;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   08-FEB-2011, sequence version 1.
DT   25-MAY-2022, entry version 19.
DE   RecName: Full=CASP-like protein 2B1;
DE            Short=ThCASPL2B1;
OS   Eutrema halophilum (Salt cress) (Sisymbrium halophilum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX   NCBI_TaxID=98038;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Shandong;
RX   PubMed=19014467; DOI=10.1186/1471-2229-8-115;
RA   Taji T., Sakurai T., Mochida K., Ishiwata A., Kurotani A., Totoki Y.,
RA   Toyoda A., Sakaki Y., Seki M., Ono H., Sakata Y., Tanaka S., Shinozaki K.;
RT   "Large-scale collection and annotation of full-length enriched cDNAs from a
RT   model halophyte, Thellungiella halophila.";
RL   BMC Plant Biol. 8:115-115(2008).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Shandong;
RX   PubMed=21106055; DOI=10.1186/1471-2229-10-261;
RA   Taji T., Komatsu K., Katori T., Kawasaki Y., Sakata Y., Tanaka S.,
RA   Kobayashi M., Toyoda A., Seki M., Shinozaki K.;
RT   "Comparative genomic analysis of 1047 completely sequenced cDNAs from an
RT   Arabidopsis-related model halophyte, Thellungiella halophila.";
RL   BMC Plant Biol. 10:261-261(2010).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=24920445; DOI=10.1104/pp.114.239137;
RA   Roppolo D., Boeckmann B., Pfister A., Boutet E., Rubio M.C.,
RA   Denervaud-Tendon V., Vermeer J.E., Gheyselinck J., Xenarios I., Geldner N.;
RT   "Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE
RT   DOMAIN PROTEIN family.";
RL   Plant Physiol. 165:1709-1722(2014).
CC   -!- SUBUNIT: Homodimer and heterodimers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Casparian strip membrane proteins (CASP)
CC       family. {ECO:0000305}.
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DR   EMBL; AK352851; BAJ33937.1; -; mRNA.
DR   AlphaFoldDB; E4MWF4; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006459; CASP/CASPL.
DR   InterPro; IPR006702; CASP_dom.
DR   Pfam; PF04535; DUF588; 1.
DR   TIGRFAMs; TIGR01569; A_tha_TIGR01569; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..199
FT                   /note="CASP-like protein 2B1"
FT                   /id="PRO_0000412063"
FT   TOPO_DOM        1..26
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        27..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        48..69
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        91..106
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        128..164
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        186..199
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   199 AA;  21263 MW;  C1E5A0C45A3A645E CRC64;
     MSYLGVGLSP VNVAGTKMKL MDRKVRLTEL ILRCSVCALA LVAAILIATD TQVKEIFTIQ
     KKAKYTDMKA LVFLVVVNGI AAAYSLLHMV RCVVGMMKGS VLFSKPLAWA IFSGDQAIAY
     LTVAGVAAAA QSAAFAKLGE PELQWMKICT IYGKFCNQVG EGIATALLAS IGMVLISSIS
     AFALFRLYGG NKAQQGSRW