ID   CSPL2_ADICA             Reviewed;         192 AA.
AC   P0DH84;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 1.
DT   25-MAY-2022, entry version 15.
DE   RecName: Full=CASP-like protein 2U1;
DE            Short=AcCASPL2U1;
OS   Adiantum capillus-veneris (Maidenhair fern).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Polypodiopsida; Polypodiidae; Polypodiales; Pteridineae; Pteridaceae;
OC   Vittarioideae; Adiantum.
OX   NCBI_TaxID=13818;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Prothallus;
RX   PubMed=15940394; DOI=10.1007/s10265-005-0209-3;
RA   Yamauchi D., Sutoh K., Kanegae H., Horiguchi T., Matsuoka K., Fukuda H.,
RA   Wada M.;
RT   "Analysis of expressed sequence tags in prothallia of Adiantum capillus-
RT   veneris.";
RL   J. Plant Res. 118:223-227(2005).
RN   [2]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=24920445; DOI=10.1104/pp.114.239137;
RA   Roppolo D., Boeckmann B., Pfister A., Boutet E., Rubio M.C.,
RA   Denervaud-Tendon V., Vermeer J.E., Gheyselinck J., Xenarios I., Geldner N.;
RT   "Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE
RT   DOMAIN PROTEIN family.";
RL   Plant Physiol. 165:1709-1722(2014).
CC   -!- SUBUNIT: Homodimer and heterodimers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Casparian strip membrane proteins (CASP)
CC       family. {ECO:0000305}.
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DR   EMBL; DK958915; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; DK962487; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; P0DH84; -.
DR   SMR; P0DH84; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006459; CASP/CASPL.
DR   InterPro; IPR006702; CASP_dom.
DR   Pfam; PF04535; DUF588; 1.
DR   TIGRFAMs; TIGR01569; A_tha_TIGR01569; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..192
FT                   /note="CASP-like protein 2U1"
FT                   /id="PRO_0000412205"
FT   TOPO_DOM        1..11
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        33..58
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        80..96
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        118..145
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        167..192
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   192 AA;  20917 MW;  A5F63CE02D61AC3A CRC64;
     MASRKQGARE GLWSMGVRLL TTLLCITSLI LLLKAKQTVR RALGLGYIAQ TVKYSDTSGF
     IYLVYINILV AAYGLIVFVS LIPSALGKSC SGKCSRWTIF VLDQVFAYVL LSAVSAATEV
     LYLADKGMSK TQWEALCPTY GFFCHMVSAS VAIGSVAVVL LAVLSVSSAQ SLFHNFYTRA
     LYTTKMRHSS LT