ID   CSPL3_PHYPA             Reviewed;         200 AA.
AC   A9STS7;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=CASP-like protein 1U2;
DE            Short=PpCASPL1U2;
GN   ORFNames=PHYPADRAFT_58644;
OS   Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC   Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX   NCBI_TaxID=3218;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Gransden 2004;
RX   PubMed=18079367; DOI=10.1126/science.1150646;
RA   Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA   Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA   Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA   Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA   Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA   Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA   Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA   Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA   Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA   Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA   Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA   Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA   Boore J.L.;
RT   "The Physcomitrella genome reveals evolutionary insights into the conquest
RT   of land by plants.";
RL   Science 319:64-69(2008).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 5-200.
RC   STRAIN=cv. Gransden 2004; TISSUE=Gametangium;
RA   Hasebe M., Nishiyama T., Suzuki Y., Sugano S., Hiwatashi Y., Kohara Y.,
RA   Shin-i T.;
RT   "Expressed genes in Physcomitrella patens.";
RL   Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=24920445; DOI=10.1104/pp.114.239137;
RA   Roppolo D., Boeckmann B., Pfister A., Boutet E., Rubio M.C.,
RA   Denervaud-Tendon V., Vermeer J.E., Gheyselinck J., Xenarios I., Geldner N.;
RT   "Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE
RT   DOMAIN PROTEIN family.";
RL   Plant Physiol. 165:1709-1722(2014).
CC   -!- SUBUNIT: Homodimer and heterodimers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Casparian strip membrane proteins (CASP)
CC       family. {ECO:0000305}.
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DR   EMBL; DS545007; EDQ65382.1; -; Genomic_DNA.
DR   EMBL; DC923681; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_001769820.1; XM_001769768.1.
DR   AlphaFoldDB; A9STS7; -.
DR   STRING; 3218.PP1S118_36V6.2; -.
DR   EnsemblPlants; Pp3c12_23940V3.1; Pp3c12_23940V3.1; Pp3c12_23940.
DR   EnsemblPlants; Pp3c12_23940V3.2; Pp3c12_23940V3.2; Pp3c12_23940.
DR   EnsemblPlants; Pp3c12_23940V3.3; Pp3c12_23940V3.3; Pp3c12_23940.
DR   Gramene; Pp3c12_23940V3.1; Pp3c12_23940V3.1; Pp3c12_23940.
DR   Gramene; Pp3c12_23940V3.2; Pp3c12_23940V3.2; Pp3c12_23940.
DR   Gramene; Pp3c12_23940V3.3; Pp3c12_23940V3.3; Pp3c12_23940.
DR   eggNOG; ENOG502RXTK; Eukaryota.
DR   HOGENOM; CLU_066104_3_0_1; -.
DR   InParanoid; A9STS7; -.
DR   OMA; NCIAFIY; -.
DR   OrthoDB; 1593533at2759; -.
DR   Proteomes; UP000006727; Chromosome 12.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006459; CASP/CASPL.
DR   InterPro; IPR006702; CASP_dom.
DR   Pfam; PF04535; DUF588; 1.
DR   TIGRFAMs; TIGR01569; A_tha_TIGR01569; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..200
FT                   /note="CASP-like protein 1U2"
FT                   /id="PRO_0000370726"
FT   TOPO_DOM        1..33
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        55..77
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        99..120
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        142..168
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        190..200
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   200 AA;  21943 MW;  F351155D9E003A87 CRC64;
     MAEPVIVVPR KGVYSDDSYH HHHRHHSFHS CTNFLLRTLT AGATAAAVVV MLISTQTSGT
     IYGYFRGRWR DYPAYKWLII ANAVVFVYSV MAAIVACFSV IARRGPLSYS PSAWLTLLVD
     FLAASALISA ASAALAVALL ARNGQDLQGT HYWPTVCNYV SKFCDYTQGA IIASFVGFGL
     LFLSTLLAAS ALYHLSHRRH