ID   CSPL4_PHYPA             Reviewed;         198 AA.
AC   A9TZ63;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=CASP-like protein 1U1;
DE            Short=PpCASPL1U1;
GN   ORFNames=PHYPADRAFT_109055;
OS   Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC   Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX   NCBI_TaxID=3218;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Villersexel 2003; TISSUE=Protonema;
RA   Richardson P., Lucas S., Rokhsar D., Wang M., Lindquist E.A.;
RT   "DOE joint genome institute Physcomitrella patens EST project.";
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Gransden 2004;
RX   PubMed=18079367; DOI=10.1126/science.1150646;
RA   Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA   Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA   Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA   Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA   Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA   Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA   Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA   Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA   Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA   Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA   Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA   Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA   Boore J.L.;
RT   "The Physcomitrella genome reveals evolutionary insights into the conquest
RT   of land by plants.";
RL   Science 319:64-69(2008).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=24920445; DOI=10.1104/pp.114.239137;
RA   Roppolo D., Boeckmann B., Pfister A., Boutet E., Rubio M.C.,
RA   Denervaud-Tendon V., Vermeer J.E., Gheyselinck J., Xenarios I., Geldner N.;
RT   "Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE
RT   DOMAIN PROTEIN family.";
RL   Plant Physiol. 165:1709-1722(2014).
CC   -!- SUBUNIT: Homodimer and heterodimers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Casparian strip membrane proteins (CASP)
CC       family. {ECO:0000305}.
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DR   EMBL; FC422259; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; DS545268; EDQ51285.1; -; Genomic_DNA.
DR   RefSeq; XP_001783888.1; XM_001783836.1.
DR   AlphaFoldDB; A9TZ63; -.
DR   STRING; 3218.PP1S381_30V6.2; -.
DR   EnsemblPlants; Pp3c10_17030V3.1; Pp3c10_17030V3.1; Pp3c10_17030.
DR   EnsemblPlants; Pp3c10_17030V3.2; Pp3c10_17030V3.2; Pp3c10_17030.
DR   EnsemblPlants; Pp3c10_17030V3.3; Pp3c10_17030V3.3; Pp3c10_17030.
DR   EnsemblPlants; Pp3c10_17030V3.4; Pp3c10_17030V3.4; Pp3c10_17030.
DR   Gramene; Pp3c10_17030V3.1; Pp3c10_17030V3.1; Pp3c10_17030.
DR   Gramene; Pp3c10_17030V3.2; Pp3c10_17030V3.2; Pp3c10_17030.
DR   Gramene; Pp3c10_17030V3.3; Pp3c10_17030V3.3; Pp3c10_17030.
DR   Gramene; Pp3c10_17030V3.4; Pp3c10_17030V3.4; Pp3c10_17030.
DR   eggNOG; ENOG502RXTK; Eukaryota.
DR   HOGENOM; CLU_066104_3_0_1; -.
DR   InParanoid; A9TZ63; -.
DR   OMA; HETTTVF; -.
DR   OrthoDB; 1593533at2759; -.
DR   Proteomes; UP000006727; Chromosome 10.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006459; CASP/CASPL.
DR   InterPro; IPR006702; CASP_dom.
DR   Pfam; PF04535; DUF588; 1.
DR   TIGRFAMs; TIGR01569; A_tha_TIGR01569; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..198
FT                   /note="CASP-like protein 1U1"
FT                   /id="PRO_0000370727"
FT   TOPO_DOM        1..30
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        52..73
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        95..117
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        139..165
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        187..198
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   198 AA;  21774 MW;  54FDCE88D05BE91F CRC64;
     MSDTPVVVIP RKGYVDGHHG YHHSYHSGLN LLLRLLQAFA TAAAVIVMLL ATQTEFTRYG
     EVRGRWRDYP AYKWFIIANA VVFVYALLAT LVACCALIAR RGPLSYSPSA WLTFLLDFVA
     ASALMSAASA ALAVALIARN GQNLQGQHYW PTFCNYVTRF CDYAQGAIIA SFCGFGLLAL
     STLLAASALH HLAWHRLH