ID   CSPL6_VITVI             Reviewed;         189 AA.
AC   A7PA04; A5C9I1; F6H448;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=CASP-like protein 1F2;
DE            Short=VvCASPL1F2;
GN   OrderedLocusNames=VIT_14s0068g01400;
GN   ORFNames=GSVIVT00037922001, GSVIVT01033020001, VIT_00033020001,
GN   VITISV_043317, Vv14s0068g01400;
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Pinot noir / PN40024;
RX   PubMed=17721507; DOI=10.1038/nature06148;
RA   Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA   Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA   Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA   Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA   Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA   Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA   Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA   Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA   Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA   Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA   Wincker P.;
RT   "The grapevine genome sequence suggests ancestral hexaploidization in major
RT   angiosperm phyla.";
RL   Nature 449:463-467(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Pinot noir;
RX   PubMed=18094749; DOI=10.1371/journal.pone.0001326;
RA   Velasco R., Zharkikh A., Troggio M., Cartwright D.A., Cestaro A., Pruss D.,
RA   Pindo M., FitzGerald L.M., Vezzulli S., Reid J., Malacarne G., Iliev D.,
RA   Coppola G., Wardell B., Micheletti D., Macalma T., Facci M., Mitchell J.T.,
RA   Perazzolli M., Eldredge G., Gatto P., Oyzerski R., Moretto M., Gutin N.,
RA   Stefanini M., Chen Y., Segala C., Davenport C., Dematte L., Mraz A.,
RA   Battilana J., Stormo K., Costa F., Tao Q., Si-Ammour A., Harkins T.,
RA   Lackey A., Perbost C., Taillon B., Stella A., Solovyev V., Fawcett J.A.,
RA   Sterck L., Vandepoele K., Grando S.M., Toppo S., Moser C., Lanchbury J.,
RA   Bogden R., Skolnick M., Sgaramella V., Bhatnagar S.K., Fontana P.,
RA   Gutin A., Van de Peer Y., Salamini F., Viola R.;
RT   "A high quality draft consensus sequence of the genome of a heterozygous
RT   grapevine variety.";
RL   PLoS ONE 2:E1326-E1326(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Muscat Hamburg; TISSUE=Fruit;
RX   PubMed=17761391; DOI=10.1016/j.gene.2007.07.016;
RA   Peng F.Y., Reid K.E., Liao N., Schlosser J., Lijavetzky D., Holt R.,
RA   Martinez Zapater J.M., Jones S., Marra M., Bohlmann J., Lund S.T.;
RT   "Generation of ESTs in Vitis vinifera wine grape (Cabernet Sauvignon) and
RT   table grape (Muscat Hamburg) and discovery of new candidate genes with
RT   potential roles in berry development.";
RL   Gene 402:40-50(2007).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=24920445; DOI=10.1104/pp.114.239137;
RA   Roppolo D., Boeckmann B., Pfister A., Boutet E., Rubio M.C.,
RA   Denervaud-Tendon V., Vermeer J.E., Gheyselinck J., Xenarios I., Geldner N.;
RT   "Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE
RT   DOMAIN PROTEIN family.";
RL   Plant Physiol. 165:1709-1722(2014).
CC   -!- SUBUNIT: Homodimer and heterodimers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Casparian strip membrane proteins (CASP)
CC       family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CCB46992.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; FN595232; CCB46992.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; FN597038; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AM487000; CAN77740.1; -; Genomic_DNA.
DR   EMBL; EC973652; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_002274297.1; XM_002274261.3.
DR   AlphaFoldDB; A7PA04; -.
DR   EnsemblPlants; Vitvi14g01489_t001; Vitvi14g01489_P001; Vitvi14g01489.
DR   GeneID; 100248101; -.
DR   Gramene; Vitvi14g01489_t001; Vitvi14g01489_P001; Vitvi14g01489.
DR   KEGG; vvi:100248101; -.
DR   eggNOG; ENOG502S695; Eukaryota.
DR   HOGENOM; CLU_066104_3_0_1; -.
DR   InParanoid; A7PA04; -.
DR   OrthoDB; 1593533at2759; -.
DR   Proteomes; UP000009183; Chromosome 14.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IBA:GO_Central.
DR   InterPro; IPR006459; CASP/CASPL.
DR   InterPro; IPR006702; CASP_dom.
DR   Pfam; PF04535; DUF588; 1.
DR   TIGRFAMs; TIGR01569; A_tha_TIGR01569; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..189
FT                   /note="CASP-like protein 1F2"
FT                   /id="PRO_0000370308"
FT   TOPO_DOM        1..27
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        49..77
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        99..113
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        135..156
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        178..189
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        169
FT                   /note="I -> T (in Ref. 3; EC973652)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   189 AA;  20472 MW;  3FC8D46BE5E70FF3 CRC64;
     MESLEVANGK SSALGVSREA SSPPQMGFFI AQVVLRFFTL AFTGAAIAVM VTAKETVEVF
     SISFTVRYSY LSAFKFLVGA DAVVCGFSML SLIFVSIFNK GKSNHYFFLY FHDLILMVLS
     MSACAAATAV GYVGRYGQDK AAWMAVCGNV KMFCDKALAS ILLSLIGFIC LFLLTIMAAR
     NLRVSGHLI