CSPL7_ARATH
ID CSPL7_ARATH Reviewed; 201 AA.
AC Q8L924; Q8W100; Q9ZQP8;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 2.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=CASP-like protein 2B2;
DE Short=AtCASPL2B2;
GN OrderedLocusNames=At2g35760; ORFNames=T20F21.5;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=24920445; DOI=10.1104/pp.114.239137;
RA Roppolo D., Boeckmann B., Pfister A., Boutet E., Rubio M.C.,
RA Denervaud-Tendon V., Vermeer J.E., Gheyselinck J., Xenarios I., Geldner N.;
RT "Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE
RT DOMAIN PROTEIN family.";
RL Plant Physiol. 165:1709-1722(2014).
CC -!- SUBUNIT: Homodimer and heterodimers. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the Casparian strip membrane proteins (CASP)
CC family. {ECO:0000305}.
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DR EMBL; AC006068; AAD15439.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC09157.1; -; Genomic_DNA.
DR EMBL; AF462840; AAL58928.1; -; mRNA.
DR EMBL; AY124824; AAM70533.1; -; mRNA.
DR EMBL; AY088673; AAM66995.1; -; mRNA.
DR PIR; F84772; F84772.
DR RefSeq; NP_565822.1; NM_129134.4.
DR AlphaFoldDB; Q8L924; -.
DR SMR; Q8L924; -.
DR BioGRID; 3492; 1.
DR PaxDb; Q8L924; -.
DR PRIDE; Q8L924; -.
DR ProteomicsDB; 224433; -.
DR EnsemblPlants; AT2G35760.1; AT2G35760.1; AT2G35760.
DR GeneID; 818148; -.
DR Gramene; AT2G35760.1; AT2G35760.1; AT2G35760.
DR KEGG; ath:AT2G35760; -.
DR Araport; AT2G35760; -.
DR TAIR; locus:2058744; AT2G35760.
DR eggNOG; ENOG502QQH2; Eukaryota.
DR HOGENOM; CLU_066104_0_1_1; -.
DR InParanoid; Q8L924; -.
DR OMA; LQWMELC; -.
DR OrthoDB; 1397007at2759; -.
DR PhylomeDB; Q8L924; -.
DR PRO; PR:Q8L924; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8L924; baseline and differential.
DR Genevisible; Q8L924; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IBA:GO_Central.
DR InterPro; IPR006459; CASP/CASPL.
DR InterPro; IPR006702; CASP_dom.
DR Pfam; PF04535; DUF588; 1.
DR TIGRFAMs; TIGR01569; A_tha_TIGR01569; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..201
FT /note="CASP-like protein 2B2"
FT /id="PRO_0000308658"
FT TOPO_DOM 1..28
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 50..71
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 93..108
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 130..166
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 167..187
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 188..201
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CONFLICT 14..17
FT /note="SGST -> TETS (in Ref. 3; AAM66995)"
FT /evidence="ECO:0000305"
FT CONFLICT 42
FT /note="A -> S (in Ref. 3; AAM66995)"
FT /evidence="ECO:0000305"
FT CONFLICT 45
FT /note="A -> S (in Ref. 3; AAM66995)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 201 AA; 21513 MW; 20CFC507EDA929AA CRC64;
MSYLGVGVSP GNVSGSTTKM KLIDRKVRVT ELILRCLVCV LALVAAILIA TDVQVREIFM
IQKKAKFTDM KALVLLVVVN GIAAGYSLVQ AVRCVVGLMK GRVLFSKPLA WAIFFGDQAV
AYLCVAGVAA AAQSAAFAKL GEPELQWMKI CNMYGKFCNQ VGEGIASALF ACIGMVLISC
ISAFGVFRLY GGSKSRPSSR W
