ID   CSPL7_SORBI             Reviewed;         461 AA.
AC   C5XEK4;
DT   09-FEB-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=CASP-like protein 4U1;
DE            Short=SbCASPL4U1;
GN   OrderedLocusNames=Sb03g029220;
OS   Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX   NCBI_TaxID=4558;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. BTx623;
RX   PubMed=19189423; DOI=10.1038/nature07723;
RA   Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA   Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA   Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA   Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA   Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA   Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA   Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman M.,
RA   Ware D., Westhoff P., Mayer K.F.X., Messing J., Rokhsar D.S.;
RT   "The Sorghum bicolor genome and the diversification of grasses.";
RL   Nature 457:551-556(2009).
RN   [2]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=24920445; DOI=10.1104/pp.114.239137;
RA   Roppolo D., Boeckmann B., Pfister A., Boutet E., Rubio M.C.,
RA   Denervaud-Tendon V., Vermeer J.E., Gheyselinck J., Xenarios I., Geldner N.;
RT   "Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE
RT   DOMAIN PROTEIN family.";
RL   Plant Physiol. 165:1709-1722(2014).
CC   -!- SUBUNIT: Homodimer and heterodimers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Casparian strip membrane proteins (CASP)
CC       family. {ECO:0000305}.
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DR   EMBL; CM000762; EES03337.1; -; Genomic_DNA.
DR   RefSeq; XP_002458217.1; XM_002458172.1.
DR   AlphaFoldDB; C5XEK4; -.
DR   STRING; 4558.Sb03g029220.1; -.
DR   EnsemblPlants; EES03337; EES03337; SORBI_3003G234800.
DR   GeneID; 8058222; -.
DR   Gramene; EES03337; EES03337; SORBI_3003G234800.
DR   KEGG; sbi:8058222; -.
DR   eggNOG; ENOG502QW75; Eukaryota.
DR   HOGENOM; CLU_046935_0_0_1; -.
DR   InParanoid; C5XEK4; -.
DR   OMA; AGDYYAH; -.
DR   OrthoDB; 1407654at2759; -.
DR   Proteomes; UP000000768; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006702; CASP_dom.
DR   Pfam; PF04535; DUF588; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..461
FT                   /note="CASP-like protein 4U1"
FT                   /id="PRO_0000391518"
FT   TOPO_DOM        1..314
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        315..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        336..354
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        355..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        376..392
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        414..431
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        432..452
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        453..461
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          1..239
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..72
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        162..192
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        193..207
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        208..239
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   461 AA;  48381 MW;  62361F3D01E19F8C CRC64;
     MASTPRTPAP VRSPPPVPTP THPTPPPPPL ETPQPPLPVS TPPPALETPP PRRVRTPPPP
     LETPPPPSPS SSQPGDEYHT PAPSLADGSP REEEASFPSD GREGGGAPAP PKSPQLSPMR
     LAAPRLLLPP PSPRTPTGQN GQEEQEGGAK AAAAGAGTGT GTAAPARQQL RLTGLARSPS
     SQRSLATTNS SPSPSPSPTP PSPLTPAAAP VVNNNSNNKN NRSGQSTPKR AAETKLPLSS
     PAATATIAVQ HFNPVEEAVT SPLHLGIGKA QRLDHHQHQH QQRQEQHAAA AAVENGGSVP
     PDVAAAVAVG ERRELSVTLR LATAVLSLAA FSVIASARTS GWAGDYYAHH LQYRYAVAVN
     VIVCAYSIAQ SFGEIRRLIS PRFIFRSMSS YYCSLFLDQA LAYLLMSASS AAASRNDLWV
     SRFGTDAFNR KITSALWLSF IAFLMLALNA LISTANLFSM L