ID   CSPL9_VITVI             Reviewed;         206 AA.
AC   A7Q6G6; F6GXF1;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=CASP-like protein 2C1;
DE            Short=VvCASPL2C1;
GN   OrderedLocusNames=VIT_11s0052g01140;
GN   ORFNames=GSVIVT00031388001, GSVIVT01029179001, VIT_00029179001,
GN   Vv11s0052g01140;
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Pinot noir / PN40024;
RX   PubMed=17721507; DOI=10.1038/nature06148;
RA   Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA   Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA   Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA   Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA   Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA   Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA   Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA   Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA   Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA   Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA   Wincker P.;
RT   "The grapevine genome sequence suggests ancestral hexaploidization in major
RT   angiosperm phyla.";
RL   Nature 449:463-467(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 14-206.
RC   STRAIN=cv. Thompson; TISSUE=Flower;
RA   Pena-Cortes H., Cuadros A., Ramirez I., Dorta F., Pinto M., Riquelme A.,
RA   Fichet T., Prieto H., Rosales M., Hinrichsen P., Gonzalez E., Poblete F.,
RA   Ruiz S.;
RT   "EST sequences from Thompson-seedless and Carmenere.";
RL   Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=24920445; DOI=10.1104/pp.114.239137;
RA   Roppolo D., Boeckmann B., Pfister A., Boutet E., Rubio M.C.,
RA   Denervaud-Tendon V., Vermeer J.E., Gheyselinck J., Xenarios I., Geldner N.;
RT   "Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE
RT   DOMAIN PROTEIN family.";
RL   Plant Physiol. 165:1709-1722(2014).
CC   -!- SUBUNIT: Homodimer and heterodimers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Casparian strip membrane proteins (CASP)
CC       family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CCB44637.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; FN594964; CCB44637.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; EE108821; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_002273403.2; XM_002273367.4.
DR   AlphaFoldDB; A7Q6G6; -.
DR   SMR; A7Q6G6; -.
DR   EnsemblPlants; Vitvi11g01671_t001; Vitvi11g01671_P001; Vitvi11g01671.
DR   GeneID; 100244426; -.
DR   Gramene; Vitvi11g01671_t001; Vitvi11g01671_P001; Vitvi11g01671.
DR   KEGG; vvi:100244426; -.
DR   eggNOG; ENOG502S20T; Eukaryota.
DR   InParanoid; A7Q6G6; -.
DR   OrthoDB; 1575732at2759; -.
DR   Proteomes; UP000009183; Chromosome 11.
DR   ExpressionAtlas; A7Q6G6; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IBA:GO_Central.
DR   InterPro; IPR006459; CASP/CASPL.
DR   InterPro; IPR006702; CASP_dom.
DR   Pfam; PF04535; DUF588; 1.
DR   TIGRFAMs; TIGR01569; A_tha_TIGR01569; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..206
FT                   /note="CASP-like protein 2C1"
FT                   /id="PRO_0000370314"
FT   TOPO_DOM        1..31
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        53..71
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        93..111
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        112..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        133..161
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        183..206
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        201..202
FT                   /note="HL -> LP (in Ref. 2; EE108821)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   206 AA;  22384 MW;  3E3DC417D7D8C9DB CRC64;
     MSVLGVGPRT VTPHLRKGMM ESSSGISLAR AEAFLRLFAI LVLVLTACLL GFDTQTKLLF
     STIKKTATFR DLGALQVVVY VDSVAAGYNL LQLGRGFISA KLKGKLINVS YVTLPWVCFL
     LDQAAVYTVF SANTAALQAS IIAVTGESSL QWMKVCNRYT RFCIQVGGAL LSGYLASLLM
     VLLSSLSAFS LFRLYSPKQF HLLKPT