CSPLF_PHYPA
ID CSPLF_PHYPA Reviewed; 179 AA.
AC A9RKK4;
DT 05-SEP-2012, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2012, sequence version 2.
DT 03-AUG-2022, entry version 53.
DE RecName: Full=CASP-like protein 5A2;
DE Short=PpCASPL5A2;
GN ORFNames=PHYPADRAFT_115765;
OS Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX NCBI_TaxID=3218;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004;
RX PubMed=18079367; DOI=10.1126/science.1150646;
RA Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA Boore J.L.;
RT "The Physcomitrella genome reveals evolutionary insights into the conquest
RT of land by plants.";
RL Science 319:64-69(2008).
RN [2]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=24920445; DOI=10.1104/pp.114.239137;
RA Roppolo D., Boeckmann B., Pfister A., Boutet E., Rubio M.C.,
RA Denervaud-Tendon V., Vermeer J.E., Gheyselinck J., Xenarios I., Geldner N.;
RT "Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE
RT DOMAIN PROTEIN family.";
RL Plant Physiol. 165:1709-1722(2014).
CC -!- SUBUNIT: Homodimer and heterodimers. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the Casparian strip membrane proteins (CASP)
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EDQ80663.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; DS544903; EDQ80663.1; ALT_INIT; Genomic_DNA.
DR RefSeq; XP_001754693.1; XM_001754641.1.
DR AlphaFoldDB; A9RKK4; -.
DR STRING; 3218.PP1S14_317V6.3; -.
DR EnsemblPlants; Pp3c6_20660V3.1; Pp3c6_20660V3.1; Pp3c6_20660.
DR EnsemblPlants; Pp3c6_20660V3.10; Pp3c6_20660V3.10; Pp3c6_20660.
DR EnsemblPlants; Pp3c6_20660V3.11; Pp3c6_20660V3.11; Pp3c6_20660.
DR EnsemblPlants; Pp3c6_20660V3.12; Pp3c6_20660V3.12; Pp3c6_20660.
DR EnsemblPlants; Pp3c6_20660V3.2; Pp3c6_20660V3.2; Pp3c6_20660.
DR EnsemblPlants; Pp3c6_20660V3.3; Pp3c6_20660V3.3; Pp3c6_20660.
DR EnsemblPlants; Pp3c6_20660V3.4; Pp3c6_20660V3.4; Pp3c6_20660.
DR EnsemblPlants; Pp3c6_20660V3.5; Pp3c6_20660V3.5; Pp3c6_20660.
DR EnsemblPlants; Pp3c6_20660V3.6; Pp3c6_20660V3.6; Pp3c6_20660.
DR EnsemblPlants; Pp3c6_20660V3.7; Pp3c6_20660V3.7; Pp3c6_20660.
DR EnsemblPlants; Pp3c6_20660V3.8; Pp3c6_20660V3.8; Pp3c6_20660.
DR EnsemblPlants; Pp3c6_20660V3.9; Pp3c6_20660V3.9; Pp3c6_20660.
DR Gramene; Pp3c6_20660V3.1; Pp3c6_20660V3.1; Pp3c6_20660.
DR Gramene; Pp3c6_20660V3.10; Pp3c6_20660V3.10; Pp3c6_20660.
DR Gramene; Pp3c6_20660V3.11; Pp3c6_20660V3.11; Pp3c6_20660.
DR Gramene; Pp3c6_20660V3.12; Pp3c6_20660V3.12; Pp3c6_20660.
DR Gramene; Pp3c6_20660V3.2; Pp3c6_20660V3.2; Pp3c6_20660.
DR Gramene; Pp3c6_20660V3.3; Pp3c6_20660V3.3; Pp3c6_20660.
DR Gramene; Pp3c6_20660V3.4; Pp3c6_20660V3.4; Pp3c6_20660.
DR Gramene; Pp3c6_20660V3.5; Pp3c6_20660V3.5; Pp3c6_20660.
DR Gramene; Pp3c6_20660V3.6; Pp3c6_20660V3.6; Pp3c6_20660.
DR Gramene; Pp3c6_20660V3.7; Pp3c6_20660V3.7; Pp3c6_20660.
DR Gramene; Pp3c6_20660V3.8; Pp3c6_20660V3.8; Pp3c6_20660.
DR Gramene; Pp3c6_20660V3.9; Pp3c6_20660V3.9; Pp3c6_20660.
DR eggNOG; ENOG502QTTS; Eukaryota.
DR HOGENOM; CLU_103961_1_0_1; -.
DR InParanoid; A9RKK4; -.
DR OMA; CTRFETS; -.
DR OrthoDB; 1282860at2759; -.
DR Proteomes; UP000006727; Chromosome 6.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR006702; CASP_dom.
DR InterPro; IPR045009; CASPL-5.
DR PANTHER; PTHR32021; PTHR32021; 1.
DR Pfam; PF04535; DUF588; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..179
FT /note="CASP-like protein 5A2"
FT /id="PRO_0000418673"
FT TOPO_DOM 1..54
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 97..114
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 115..135
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 136..154
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 155..175
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 176..179
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 179 AA; 18991 MW; 3C90A31BEEAB153F CRC64;
MEATSHPAVH PVAVPPQFQG AGPPAIQMKD FPGSPGTAGG LALRFTQFGF SLISLCIMVS
IAGFSSVTAF CFLVATMVFQ CIWSLCLGAL DIYALLTQRS FRNPLIVSLF VVGDWVTSTM
TFAGACAAAG ITVLIDNDLE QCGPNHCGRF EAAAAMAFMS WTATTLSFCL SFWLLASCR
