CSPLG_ARATH
ID CSPLG_ARATH Reviewed; 152 AA.
AC Q8L7R5; Q9LTC8;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=CASP-like protein 5B3;
DE Short=AtCASPL5B3;
GN OrderedLocusNames=At3g23200; ORFNames=K14B15.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, SUBCELLULAR LOCATION, GENE FAMILY,
RP AND NOMENCLATURE.
RX PubMed=24920445; DOI=10.1104/pp.114.239137;
RA Roppolo D., Boeckmann B., Pfister A., Boutet E., Rubio M.C.,
RA Denervaud-Tendon V., Vermeer J.E., Gheyselinck J., Xenarios I., Geldner N.;
RT "Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE
RT DOMAIN PROTEIN family.";
RL Plant Physiol. 165:1709-1722(2014).
CC -!- SUBUNIT: Homodimer and heterodimers. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:24920445};
CC Multi-pass membrane protein {ECO:0000269|PubMed:24920445}.
CC -!- TISSUE SPECIFICITY: Expressed in the stele of the root and in leaves.
CC {ECO:0000269|PubMed:24920445}.
CC -!- DEVELOPMENTAL STAGE: Present in the root maturation zone, and in
CC lateral root primordia. Expressed in two parallel files that are
CC probably xylem pole pericycle cells. In leaves, detected in files of
CC cells parallel to the vasculature. {ECO:0000269|PubMed:24920445}.
CC -!- SIMILARITY: Belongs to the Casparian strip membrane proteins (CASP)
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA95733.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB025608; BAA95733.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE76734.1; -; Genomic_DNA.
DR EMBL; AY128308; AAM91511.1; -; mRNA.
DR EMBL; BT006540; AAP21348.1; -; mRNA.
DR RefSeq; NP_188961.2; NM_113221.3.
DR AlphaFoldDB; Q8L7R5; -.
DR PaxDb; Q8L7R5; -.
DR EnsemblPlants; AT3G23200.1; AT3G23200.1; AT3G23200.
DR GeneID; 821898; -.
DR Gramene; AT3G23200.1; AT3G23200.1; AT3G23200.
DR KEGG; ath:AT3G23200; -.
DR Araport; AT3G23200; -.
DR TAIR; locus:2086258; AT3G23200.
DR eggNOG; ENOG502RYAJ; Eukaryota.
DR HOGENOM; CLU_103961_1_0_1; -.
DR InParanoid; Q8L7R5; -.
DR OMA; GEECTKF; -.
DR OrthoDB; 1523420at2759; -.
DR PhylomeDB; Q8L7R5; -.
DR PRO; PR:Q8L7R5; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8L7R5; baseline and differential.
DR Genevisible; Q8L7R5; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IDA:UniProtKB.
DR InterPro; IPR006702; CASP_dom.
DR InterPro; IPR045009; CASPL-5.
DR PANTHER; PTHR32021; PTHR32021; 1.
DR Pfam; PF04535; DUF588; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..152
FT /note="CASP-like protein 5B3"
FT /id="PRO_0000308669"
FT TOPO_DOM 1..21
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 64..77
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 99..127
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 149..152
FT /note="Extracellular"
FT /evidence="ECO:0000255"
SQ SEQUENCE 152 AA; 16092 MW; D1A8370B1329E272 CRC64;
MIDIPGTPGT LTGLVLRISQ CVFAAGSISY MVTSGGFFSF TAFCYLIAAM GLQVIWSFGL
AILDTFALVR KKTLLSPVLV SLFVVGDWVT STLSLAGASS SAGITVLYFG DLGSCSFEAE
CWKYQLSVAL AFLCWITIAV SSLTTLWLLA SA
