ID   CSPLM_MAIZE             Reviewed;         181 AA.
AC   P0DI66;
DT   05-SEP-2012, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2012, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=CASP-like protein 5A2;
DE            Short=ZmCASPL5A2;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. B73; TISSUE=Leaf meristem, and Shoot meristem;
RA   Chen H.D., Zhang X., Zhou R.L., Arias L.A.C., Shendelman J.M.,
RA   Zazubovits N., Borsuk L.A., Emrich S.J., Ashlock D.A., Scanlon M.J.,
RA   Schnable P.S.;
RT   "Expressed sequence tags from B73 Maize shoot apical meristems.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=24920445; DOI=10.1104/pp.114.239137;
RA   Roppolo D., Boeckmann B., Pfister A., Boutet E., Rubio M.C.,
RA   Denervaud-Tendon V., Vermeer J.E., Gheyselinck J., Xenarios I., Geldner N.;
RT   "Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE
RT   DOMAIN PROTEIN family.";
RL   Plant Physiol. 165:1709-1722(2014).
CC   -!- SUBUNIT: Homodimer and heterodimers. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Casparian strip membrane proteins (CASP)
CC       family. {ECO:0000305}.
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DR   EMBL; DN223413; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_008652123.1; XM_008653901.1.
DR   AlphaFoldDB; P0DI66; -.
DR   STRING; 4577.GRMZM2G086604_P01; -.
DR   PaxDb; P0DI66; -.
DR   EnsemblPlants; Zm00001eb007310_T001; Zm00001eb007310_P001; Zm00001eb007310.
DR   GeneID; 103632043; -.
DR   Gramene; Zm00001eb007310_T001; Zm00001eb007310_P001; Zm00001eb007310.
DR   KEGG; zma:103632043; -.
DR   eggNOG; ENOG502QTTS; Eukaryota.
DR   HOGENOM; CLU_103961_0_0_1; -.
DR   OMA; CWFTALP; -.
DR   OrthoDB; 1282860at2759; -.
DR   Proteomes; UP000007305; Chromosome 1.
DR   ExpressionAtlas; P0DI66; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006702; CASP_dom.
DR   InterPro; IPR045009; CASPL-5.
DR   PANTHER; PTHR32021; PTHR32021; 1.
DR   Pfam; PF04535; DUF588; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..181
FT                   /note="CASP-like protein 5A2"
FT                   /id="PRO_0000418703"
FT   TOPO_DOM        1..38
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        60..77
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        99..115
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        137..153
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        154..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        175..181
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   181 AA;  19044 MW;  3B322E14C0A5E21B CRC64;
     MFASRPVVHP LEVAAPAHPV QQPAPGVLMK DLPGMPGTPG GLGLRVLQLL FAAISLAVMS
     STADFASVSA FCYLITTTVL QCVWSLTVAI VDIYALLVKR CLRNRRAVTL FSIGDGITWL
     VSLSGACAAA GITVLIDADL IMCSENPCAS FQTAVAMGFM CCFSLLPSFL LNFYSIASSH
     G